Turkiye Klinikleri Journal of Dermatology

.: ORIGINAL RESEARCH
Diffüz Saç Dökülmesi Olan Kadın Hastalarda Serum Demir, Ferritin, Çinko ve Folik Asit Düzeylerinin Değerlendirilmesi
Evaluation of Serum Iron, Ferritin, Zinc and Folic Acid Levels in Female Patients with Diffuse Hair Loss
Yeşim AKPINAR KARAa
aDeri ve Zührevi Hastalıkları Kliniği, Ankara Liv Hospital, Ankara, TÜRKİYE
Turkiye Klinikleri J Dermatol. 2019;29(2):75-9
doi: 10.5336/dermato.2019-66412
Article Language: TR
Full Text
ÖZET
Amaç: Diffüz saç dökülmesi kadınlarda en sık görülen saç hastalıklarından biridir ve etiyolojisinde pek çok faktör rol oynamaktadır .Bu çalışmanın amacı, diffüz tipte saç dökülmesi olan kadın hastalarda serum demir, ferritin, çinko ve folik asit düzeylerinin rolünü araştırmaktır. Gereç ve Yöntemler: Bu çalışmada Ekim 2017-Mayıs 2018 tarihleri arasında dermatoloji polikliniğine başvuran, son 6 aydır skar yapmayan saç dökülmesi olan 60 kadın hasta ile 60 sağlıklı kadın (kontrol grubu) incelendi. Kontrol grubu, nevus şikâyeti ile başvuran ve saç dökülmesi olmayan bireylerin dosyalarından retrospektif olarak taranarak oluşturuldu. İki grupta da sistemik hastalığı ve ilaç kullanım öyküsü olan bireyler ile gebelik, emzirme döneminde olan hastalar çalışma dışı bırakıldı. Her iki grubun serum demir, ferritin, çinko ve folik asit değerleri istatistiksel olarak karşılaştırıldı. Bulgular: Hasta grubunun yaş ortalaması 34,3 (17-53) yıl, kontrol grubunun ise 30,5 (16-56) yıl idi. Saç dökülmesi olan grupta, kontrol grubuna göre serum çinko ve folik asit düzeylerinin ortalaması daha düşük olmasına rağmen istatistiksel olarak anlamlı bir fark yoktu (p>0,05). Saç dökülmesi olan grupta kontrol grubuna göre serum demir, ferritin düzeylerinin ortalaması daha yüksek saptandı, fakat istatistiksel olarak anlamlı bir fark bulunamadı. (p>0,05). Sonuç: Saç dökülmesi yakınmasıyla gelen kadın hastalarda demir eksikliği anemisi, folat ve çinko eksikliği hastalığa neden olabilecek faktörler olarak düşünülmektedir. Laboratuvar testlerinde bir eksiklik tespit edilmediğinde, çinko, folik asit ve demir içeren preparatlarla tedavi uygulamasının etkisiz ve gereksiz olacağını düşünüyoruz.

Anahtar Kelimeler: Diffüz saç dökülmesi; demir; ferritin; çinko; folik asit
ABSTRACT
Objective: Diffuse hair loss is one of the most common hair diseases in women and multiple factors play role in ethiopathogenesis of this disease. The aim of this study was to investigate the role of serum vitamin levels in female patients with diffuse hair loss. Material and Methods:We retrospectively evaluated medical data of patients who were admitted to the dermatology outpatient clinic at hospital between October 2017-May 2018 with a diagnosis of diffuse hair loss. 60 patients with hair loss in the last six months and 60 controls were included in the study. The control group was created retrospectively from medical records of individuals who followed up with nevus and no complaints of hair loss. In the both groups, individuals with history of other systemic disease and drug intake, pregnancy, lactation period were excluded. Serum vitamin levels of both groups were statistically compared. Results: The mean age of the patient group was 34.3 year (17 to 53 year old) and the mean age of the control group was 30.5 year (16 to 56 year old). Although the mean serum zinc and folic acid levels were lower in the group with hair loss compared to the control group, there was no statistically significant difference (p>0.05). Mean serum iron and ferritin levels were higher in hair loss group than control group but no statistically significant difference was found. Conclusion: Iron deficiency anemia, folate, and zinc deficiency are thought to be factors that can cause disease in female patients with the complaint of hair loss. When we do not find a deficiency in laboratory tests, we think that the administration of zinc and folic acid and iron-containing preparations will be ineffective and unnecessary.

Keywords: Diffuse hair loss; iron; ferritin; zinc; folic acid
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