Turkiye Klinikleri Journal of Pediatrics

.: REVIEW
Yenidoğanlarda Sık Görülen Oral Lezyonlar ve Tedavileri
Common Oral Lesions and Their Treatment in Newborns
Umutcan DEMİRALa, Meral ÜNÜRa
aAğız, Diş ve Çene Cerrahisi ABD, İstanbul Üniversitesi Diş Hekimliği Fakültesi, İstanbul, TÜRKİYE
Turkiye Klinikleri J Pediatr. 2019;28(3):128-38
doi: 10.5336/pediatr.2019-66189
Article Language: TR
Full Text
ÖZET
 Yenidoğanlarda oral lezyonlar nadir olarak görülse de diş hekimlerini, pediatristleri ve dermatologları yakından ilgilendirmektedir. Bu oral lezyonların sınıflandırılması için çalışmalar yapılmış, ancak standart bir tedavi rejimi ve genel kabul görmüş bir sınıflama yapılmamıştır. Yenidoğanların ağızları pek çok özelliği bakımından özgündür ve doğum periyodundaki gelişimsel olaylara bağlı olarak meydana gelen lezyonlar genellikle iyi huylu mukozal durumları içermektedir. Çalışmalarda; Bohn nodülleri, Epstein incileri ve gingival kistler en sık görülen kistik lezyonlar iken, enfeksiyona bağlı olarak en çok kandida ve herpes simpleks virüsleri ile ilişkili orolabial lezyonlar görülmektedir. Ek olarak, travmaya bağlı lezyonlar, hemanjiyom, lenfanjiyom, konjenital epulis gibi tümöral durumlar, pemfigus vulgaris gibi otoimmün hastalıklar, coğrafi dil, ankiloglossi, makroglossi gibi benign durumlar ve malign melanom ve rabdomiyosarkom gibi malign neoplazmalar da oral bölgelerde gözlenebilmektedir. Oral mukozal lezyonlar, özellikle yenidoğanlarda ve çocuklarda sistemik hastalıkların erken teşhisi için ipucu olabilir. Bundan dolayı yanlış tedavi ve araştırmalardan kaçınmak, doğru tanıya ulaşmak için görülebilecek tüm lezyonlar hakkında bilgi sahibi olmak gerekmektedir. Oral bölgede meydana gelen bir lezyonda endişeli ebeveynlerin başvuracağı merkezlerin başında diş hekimleri gelmektedir. Bunun yanında, yenidoğan oral lezyonlarıyla ilgili literatürdeki çalışma sayısı oldukça azdır ve bu çalışmada, klinikte karşımıza çıkabilecek lezyonlar, bu lezyonların görülme sıklıkları, etiyolojileri, klinik bulguları, ayırıcı tanıları ve tedavi yöntemlerinin bir araya toplanması amaçlanmıştır.

Anahtar Kelimeler: Yenidoğan; ağız mukozası; ağız hastalıkları; ağız neoplazileri
ABSTRACT
 Oral lesions are rarely seen in neonates, but they are closely related to dentists, pediatricians and dermatologists. Studies have been conducted to classify these oral lesions, but a standard treatment regimen and a generally accepted classification have not been performed. Newborns' mouths are unique in terms of many features, and the lesions that occur due to developmental events in the period of birth usually involve benign mucosal conditions. While Bohn's nodules, Epstein pearls and gingival cysts are the most frequently observed cystic lesions in studies, orabial lesions related to candida and herpes simplex viruses are mostly observed in relation to infection. In addition to these, tumoral cases such as lesions caused by trauma, hemangioma, lymphangioma and congenital epulis; autoimmune illnesses such as pemphigus vulgaris; benign situations such as geographical tongue, ankyloglossia, macroglossia and malign neoplasms such as malignant melanoma and rhabdomyosarcoma are also observed in oral areas. Oral mucosal lesions may be a clue for early diagnosis of systemic diseases, especially in newborns and children. Therefore, it is necessary to avoid inappropriate treatment and investigation and to have information about all the lesions that can be seen in order to reach the correct diagnosis. In the case of a lesion that occurs in the oral region, dentists are the primary centers of concern for parents. In addition, the number of studies on neonatal oral lesions in the literature is very few, and in this review, the lesions that may be encountered in the clinic, the incidence, etiology, clinical findings, differential diagnoses and treatment methods of these lesions were collected.

Keywords: Newborn; mouth mucosa; mouth diseases; mouth neoplasms
REFERENCES:
  1. Bilodeau EA, Collins BM. Odontogenic cysts and neoplasms. Surg Pathol Clin. 2017;10(1):177-222. [Crossref]  [PubMed] 
  2. Kula KS, Josell SD. Oral problems. In: McMillan JA, Feigin RD, DeAngelis CD, eds. Oski's Pediatrics: Principles and Practice. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p.781-800.
  3. George D, Bhat SS, Hegde SK. Oral findings in newborn children in and around Mangalore, Karnataka State, India. Med Princ Pract. 2008;17(5):385-9. [Crossref]  [PubMed] 
  4. Yilmaz AE, Gorpelioglu C, Sarifakioglu E, Dogan DG, Bilici M, Celik N. Prevalence of oral mucosal lesions from birth to two years. Niger J Clin Pract. 2011;14(3):349-53. [Crossref]  [PubMed] 
  5. Rajendra R, Sivapathasundharam B. Shafer's Textbook of Oral Pathology. 6th ed. New Delhi: Elsevier; 2009. p.963.
  6. Cizmeci MN, Kanburoglu MK, Kara S, Tatli MM. Bohn's nodules: peculiar neonatal intraoral lesions mistaken for natal teeth. Eur J Pediatr. 2014;173(3):403. [Crossref]  [PubMed] 
  7. Shear M, Speight P. Cysts of the oral and maxillofacial regions. 4th ed. Oxford: Blackwell Munksgaard; 2007. p.238. [Crossref] 
  8. Moda A. Gingival cyst of newborn. Int J Clin Pediatr Dent. 2011;4(1):83-4. [Crossref]  [PubMed]  [PMC] 
  9. Haveri FT, Inamadar AC. A cross-sectional prospective study of cutaneous lesions in newborn. ISRN Dermatol. 2014;2014:360590. [Crossref]  [PubMed]  [PMC] 
  10. Patil S, Rao RS, Majumdar B, Jafer M, Maralingannavar M, Sukumaran A. Oral lesions in neonates. Int J Clin Pediatr Dent. 2016;9(2):131-8. [Crossref]  [PubMed]  [PMC] 
  11. Singh RK, Kumar R, Pandey RK, Singh K. Dental lamina cysts in a newborn infant. BMJ Case Rep. 2012;2012. [Crossref]  [PubMed]  [PMC] 
  12. Kates GA, Needleman HL, Holmes LB. Natal and neonatal teeth: a clinical study. J Am Dent Assoc. 1984;109(3):441-3. [Crossref]  [PubMed] 
  13. King NM, Lee AM. Prematurely erupted teeth in newborn infants. J Pediatr. 1989;114(5):807-9. [Crossref] 
  14. Aleman Navas RM, Martinez Mendoza MG, Leonardo MR, Silva RA, Herrera HW, Herrera HP. Congenital eruption cyst: a case report. Braz Dent J. 2010;21(3):259-62. [Crossref]  [PubMed] 
  15. Park SW, Lee JJ, Chae SA, Yoo BH, Kim GJ, Lee SY. Congenital epidermoid cyst of the oral cavity: prenatal diagnosis by sonography. Clin Exp Otorhinolaryngol. 2013;6(3):191-3. [Crossref]  [PubMed]  [PMC] 
  16. Mohta A, Sharma M. Congenital oral cysts in neonates: report of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102(5):e36-8. [Crossref]  [PubMed] 
  17. Benjamin DK Jr, Stoll BJ, Gantz MG, Walsh MC, Sanchez PJ, Das A, et al. Neonatal candidiasis: epidemiology, risk factors, and clinical judgment. Pediatrics. 2010;126(4):e865-73. [Crossref]  [PubMed]  [PMC] 
  18. Tinoco-Araujo JE, Araujo DF, Barbosa PG, Santos PS, Medeiros AM. Invasive candidiasis and oral manifestations in premature newborns. Einstein (Sao Paulo). 2013;11(1):71-5. [Crossref]  [PMC] 
  19. De Castro AL, Lesoes Brancas. In: De Castro AL, Moraes NP, Furuse TA. Estomatologia: Lesoes Brancas. 2nd ed. Sao Paulo: Livraria Santos; 1995. p.106-17.
  20. Sonis A. Doencas de boca e manifestacoes orais de doencas sistemicas. In: Pinkham JR, ed. Odontopediatria da Infancia a Adolescencia. 2nd ed. Sao Paulo: Artes Medicas; 1996. p.77-92.
  21. George MH. Hepato-adrenal necrosis with intranuclear inclusion bodies. Am J Pathol. 1935;11(1):127-42.
  22. Kimberlin DW. Neonatal herpes simplex infection. Clin Microbiol Rev. 2004;17(1):1-13. [Crossref]  [PubMed]  [PMC] 
  23. De Boeck H. Osteomyelitis and septic arthritis in children. Acta Orthop Belg. 2005;71(5):505-15.
  24. avedra-Lozano J, Mejias A, Ahmad N, Peromingo E, Ardura MI, Guillen S, et al. Changing trends in acute osteomyelitis in children: impact of methicillin-resistant Staphylococcus aureus infections. J Pediatr Orthop. 2008;28(5):569-75. [Crossref]  [PubMed] 
  25. Polin R, Spitzer A. Fetal and Neonatal Secrets. 3rd ed. Philadelphia: Saunders, Elsevier; 2014. p.576.
  26. Unur M, Onur OD. Agiz Hastaliklarininn Tani ve Tedavisi. 2. Baski. Istanbul: Quintessence Yayincilik; 2008. p.368.
  27. Bodner L, Manor E, Joshua BZ, Shaco-Levy R. Oral mucoceles in children--analysis of 56 new cases. Pediatr Dermatol. 2015;32(5):647-50. [Crossref]  [PubMed] 
  28. Gatti AF, Moreti MM, Cardoso SV, Loyola LV. Mucus extravasation phenomenon in newborn babies: report of two cases. Int J Paediatr Dent. 2001;11(1):74-7. [Crossref]  [PubMed] 
  29. Nguyen BN, Malone BN, Sidman JD, Barnett Roby B. Excision of sublingual gland as treatment for ranulas in pediatric patients. Int J Pediatr Otorhinolaryngol. 2017;97:154-6. [Crossref]  [PubMed] 
  30. Onderoglu L, Saygan-Karamursel B, Deren O, Bozdag G, Teksam O, Tekinalp G. Prenatal diagnosis of ranula at 21 weeks of gestation. Ultrasound Obstet Gynecol. 2003;22(4):399-401. [Crossref]  [PubMed] 
  31. Singh GB, Rai AK, Arora R, Garg S, Abbey P, Shukla S. A rare case of congenital simple cystic ranula in a neonate. Case Rep Otolaryngol. 2013;2013:841930. [Crossref]  [PubMed]  [PMC] 
  32. Costacurta M, Maturo P, Docimo R. Riga-Fede disease and neonatal teeth. Oral Implantol (Rome). 2012;5(1):26-30.
  33. Domingues-Cruz J, Herrera A, Fernandez-Crehuet P, Garcia-Bravo B, Camacho F. Riga-Fede disease associated with postanoxic encephalopathy and trisomy 21: a proposed classification. Pediatr Dermatol. 2007;24(6):663-5. [Crossref]  [PubMed] 
  34. van der Meij EH, de Vries TW, Eggink HF, de Visscher JG. Traumatic lingual ulceration in a newborn: Riga-Fede disease. Ital J Pediatr. 2012;38:20. [Crossref]  [PubMed]  [PMC] 
  35. Rao RS, Mathad SV. Natal teeth: case report and review of literature. J Oral Maxillofac Pathol. 2009;13(1):41-6. [Crossref]  [PubMed]  [PMC] 
  36. Kiat-Amnuay S, Bouquot J. Breastfeeding keratosis: this frictional keratosis of newborns may mimic thrush. Pediatrics. 2013;132(3):e775-8. [Crossref]  [PubMed] 
  37. Barnes L. Surgical Pathology of the Head and Neck. Vol 2. 2nd ed. New York: Marcel Dekker; 2001. p.2243.
  38. North PE. Pediatric vascular tumors and malformations. Surg Patho Clin. 2010;3(3):455-94. [Crossref]  [PubMed] 
  39. Zheng JW, Zhang L, Zhou Q, Mai HM, Wang YA, Fan XD, et al. A practical guide to treatment of infantile hemangiomas of the head and neck. Int J Clin Exp Med. 2013;6(10):851-60.
  40. Neville BW, Damm DD. Allen CM, Bouquot JE. Oral and Maxillofacial Pathology. 3rd ed. New Delhi: Saunders, Elsevier; 2009. p.968.
  41. Kolay SK, Jha PK, Sinha RK, Kumar P. Oral lymphangioma: a review. J Clin Den Res Edu. 2012;1(1):42-6.
  42. Lee JM, Kim UK, Shin SH. Multiple congenital epulis of the newborn: a case report and literature review. J Ped Surg Case Rep. 2013;1(3):32-3. [Crossref] 
  43. McGuire TP, Gomes PP, Freilich MM, Sandor GK. Congenital epulis: a surprise in the neonate. J Can Dent Assoc. 2006;72(8):747-50.
  44. Tombak A, Tiftik EN. [Langerhans cell histiocytosis]. Turkiye Klinikleri J Hematol-Special Topics. 2013;6(1):74-9.
  45. Martinez DSM, Villagran UJ, Ajqui RR, Cervantes CK. Oral manifestations of Langerhans cell histiocytosis (LHC): review of scientific literature and case report. Rev Odontol Mex. 2012;16(2):123-30.
  46. Stein SL, Paller AS, Haut PR, Mancini AJ. Langerhans cell histiocytosis presenting in the neonatal period: a retrospective case series. Arch Pediatr Adolesc Med. 2001;155(7):778-83. [Crossref]  [PubMed] 
  47. Hamilton S, Macrae D, Agrawal S, Matic D. Melanotic neuroectodermal tumour of infancy. Can J Plast Surg. 2008;16(1):41-4. [Crossref]  [PubMed]  [PMC] 
  48. Kruse-Losler B, Gaertner C, Burger H, Seper L, Joos U, Kleinheinz J. Melanotic neuroectodermal tumor of infancy: systematic review of the literature and presentation of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102(2):204-16. [Crossref]  [PubMed] 
  49. Calda P, Novotna M, Cutka D, Brest'ak M, Haslik L, Goldova B, et al. A case of an epignathus with intracranial extension appearing as a persistently open mouth at 16 weeks and subsequently diagnosed at 20 weeks of gestation. J Clin Ultrasound. 2011;39(3):164-8. [Crossref]  [PubMed] 
  50. Clement K, Chamberlain P, Boyd P, Molyneux A. Prenatal diagnosis of an epignathus: a case report and review of the literature. Ultrasound Obstet Gynecol. 2001;18(2):178-81. [Crossref]  [PubMed] 
  51. Vawter GF, Tefft M. Congenital tumors of the parotid gland. Arch Pathol. 1966;82(3):242-5.
  52. Taylor GP. Congenital epithelial tumor of the parotid-sialoblastoma. Pediatr Pathol. 1988;8(4):447-52. [Crossref]  [PubMed] 
  53. Hart I. Tumours of the Fetus and Infant: an Atlas. 1st ed. New York: Springer-Verlag; 2002. p.327.
  54. Amer YB, Al Ajroush W. Pemphigus vulgaris in a neonate. Ann Saudi Med. 2007;27(6):453-5. [Crossref]  [PubMed]  [PMC] 
  55. Neville BW, Damm DD, Allen CM, Chi AC. Oral and Maxillofacial Pathology. 4th ed. Elsevier; 2016. p.928.
  56. Manipon C. Ankyloglossia and the breastfeeding infant: assessment and intervention. Adv Neonatal Care. 2016;16(2):108-13. [Crossref]  [PubMed] 
  57. Bezerra S, Costa I. Oral conditions in children from birth to 5 years: the findings of a children's dental program. J Clin Pediatr Dent. 2000;25(1):79-81. [Crossref]  [PubMed] 
  58. Bessa CF, Santos PJ, Aguiar MC, do Carmo MA. Prevalence of oral mucosal alterations in children from 0 to 12 years old. J Oral Pathol Med. 2004;33(1):17-22. [Crossref] 

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-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

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