Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Ağız Gargaralarının Reçine İnfiltrantın Renklenmesi Üzerine Etkileri: Bir İn Vitro Çalışma
The Effects of Mouthwashes on the Discoloration of Resin Infiltrant: An In Vitro Study
Emel KARAMANa , Feyza Otan ÖZDENb , Betül Kübra KURUCU KARADENİZc , Merve NİGİZd
aOndokuz Mayıs Üniversitesi Diş Hekimliği Fakültesi, Restoratif Diş Tedavisi ABD, Samsun, Türkiye
bOndokuz Mayıs Üniversitesi Diş Hekimliği Fakültesi, Periodontoloji ABD, Samsun, Türkiye
cGiresun Üniversitesi Diş Hekimliği Fakültesi, Restoratif Diş Tedavisi ABD, Giresun, Türkiye
dSerbest Diş Hekimi, Kocaeli, Türkiye
Turkiye Klinikleri J Dental Sci. 2024;30(1):124-31
doi: 10.5336/dentalsci.2023-98956
Article Language: TR
Full Text
ÖZET
Amaç: Ağız gargaraları, profesyonel öneri doğrultusunda veya profesyonel öneri olmadan hastalar tarafından yaygın olarak kullanılmaktadır. Uzun süreli ağız gargarası kullanımı, reçine restorasyonların dışsal renklenmesine neden olabilmektedir. Bu çalışmanın amacı, farklı ağız gargaralarının ve uzun süreli kullanımlarının Icon reçine infiltrantın renk stabilitesine etkisini in vitro olarak değerlendirmektir. Gereç ve Yöntemler: Silindir şeklinde teflon kalıplar kullanılarak, 8 mm çapında ve 1 mm yüksekliğinde 75 adet Icon reçine infiltrant örneği hazırlandı ve daldırma ortamına göre rastgele 5 gruba ayrıldı: distile su (kontrol), Listerine Cool Mint, Klorhex, Meridol ve DentaSave. Örneklerin renk parametreleri başlangıçta ve 7, 14, 21 ve 28. günlerin sonunda bir spektrofotometre (SpectroShade; Medical High Technologies, İtalya) yardımı ile ölçüldü. ΔE00 değerleri hesaplandı ve istatistiksel olarak analiz edildi. Bulgular: Deneyin sonunda daldırma ortamının renklendirme potansiyeli açısından DentaSave en yüksek renklendirme potansiyeline sahipti ve bunu sırasıyla Listerine Cool Mint, Meridol, Klorhex ve distile su izlemiştir. Tüm gargara grupları, kontrol grubuna göre daha yüksek renk değişimine sebep olmuştur (p<0,05). Tüm test gruplarının ΔE00 değerleri zaman içerisinde artış göstermiştir (p<0,05). Sonuç: Ağız gargaraları, Icon reçine için renklendirme potansiyeli göstermektedir. Ağız gargaralarına uzun süre maruz kalmak renklenme şiddetinin artmasına neden olmaktadır. Klinisyenler ve hastalar, reçine infiltrasyonunun sağladığı estetik sonucun sürdürülmesi için günlük olarak kullanılan ağız gargaralarının renklendirme potansiyelinin farkında olmalıdır.

Anahtar Kelimeler: Ağız gargarası; reçine infiltrant; dental materyaller; renklenme
ABSTRACT
Objective: Mouthrinses are widely used by patients with or without professional recommendations and prolonged use of mouthrinses may cause extrinsic staining of resin restorations. The aim of this in vitro study was to evaluate different mouthrinses and prolonged exposure on the color stability of Icon resin infiltrant. Material and Methods: Seventy five disk-shaped specimens of Icon 8 mm in diameter and 1 mm in hight were prepared using a customized cylindrical Teflon mould and randomly divided into 5 groups according to the immersion medium: distilled water (control), Listerine Cool Mint, Klorhex, Meridol, and Denta Save. Color parameters were measured with a spectrophotometer (SpectroShade; Medical High Technologies, Italy) at baseline and at the end of 7, 14, 21, and 28 days. ΔE00 values were calculated and evaluated statistically. Results: At the end of the experiment DentaSave had the highest staining potential, followed by Listerine Cool Mint, Meridol and Klorhex, respectively. All test groups showed discoloration over the clinically acceptable threshold (p<0.05). The ΔE00 values of all the test groups increased within time (p<0.05). Conclusion: Mouthrinses have staining potential for Icon. Longer exposures to mouthrinses cause more severe staining. Clinicians and patients should be aware of the staining potential of mouthrinses used daily for the maintenance of the esthetic outcome provided by resin infiltrant.

Keywords: Mouthwashes; resin infiltrant; dental materials; staining
REFERENCES:
  1. Frencken JE, Sharma P, Stenhouse L, Green D, Laverty D, Dietrich T. Global epidemiology of dental caries and severe periodontitis - a comprehensive review. J Clin Periodontol. 2017;44 Suppl 18:S94-S105. [Crossref]  [PubMed] 
  2. Bergstrand F, Twetman S. A review on prevention and treatment of post-orthodontic white spot lesions - evidence-based methods and emerging technologies. Open Dent J. 2011;5:158-62. [Crossref]  [PubMed]  [PMC] 
  3. Kidd EA, Fejerskov O. What constitutes dental caries? Histopathology of carious enamel and dentin related to the action of cariogenic biofilms. J Dent Res. 2004;83 Spec No C:C35-8. [Crossref]  [PubMed] 
  4. Kau CH, Wang J, Palombini A, Abou-Kheir N, Christou T. Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: A randomized trial. Angle Orthod. 2019;89(3):365-71. [Crossref]  [PubMed]  [PMC] 
  5. Thierens LAM, Moerman S, Elst CV, Vercruysse C, Maes P, Temmerman L, et al. The in vitro remineralizing effect of CPP-ACP and CPP-ACPF after 6 and 12 weeks on initial caries lesion. J Appl Oral Sci. 2019;27:e20180589. [Crossref]  [PubMed]  [PMC] 
  6. Zantner C, Martus P, Kielbassa AM. Clinical monitoring of the effect of fluorides on long-existing white spot lesions. Acta Odontol Scand. 2006;64(2):115-22. [Crossref]  [PubMed] 
  7. Dogra S, Goyal V, Gupta A, Joshi S, Kataria V, Saini J, et al. Spectrophotometric evaluation of color change in tooth enamel defects using resin infiltrate: an ın vivo study. Int J Clin Pediatr Dent. 2020;13(2):150-4. [Crossref]  [PubMed]  [PMC] 
  8. Paris S, Meyer-Lueckel H. Inhibition of caries progression by resin infiltration in situ. Caries Res. 2010;44(1):47-54. [Crossref]  [PubMed] 
  9. Faghihian R, Shirani M, Tarrahi MJ, Zakizade M. Efficacy of the Resin Infiltration Technique in Preventing Initial Caries Progression: A Systematic Review and Meta-Analysis. Pediatr Dent. 2019;41(2):88-94. [PubMed] 
  10. Kugel G, Arsenault P, Papas A. Treatment modalities for caries management, including a new resin infiltration system. Compend Contin Educ Dent. 2009;30 Spec No 3:1-10; quiz 11-2. [Crossref]  [PubMed] 
  11. Coelho ASEC, Paula ABP, Carrilho TMP, da Silva MJRF, Botelho MFRR, Carrilho EVVF. Chlorhexidine mouthwash as an anticaries agent: A systematic review. Quintessence Int. 2017;48(7):585-91. [PubMed] 
  12. Cengiz S, Yüzbaşioğlu E, Cengiz MI, Velioğlu N, Sevimli G. Color stability and surface roughness of a laboratory-processed composite resin as a function of mouthrinse. J Esthet Restor Dent. 2015;27(5):314-21. [Crossref]  [PubMed] 
  13. Tartaglia GM, Kumar S, Fornari CD, Corti E, Connelly ST. Mouthwashes in the 21st century: a narrative review about active molecules and effectiveness on the periodontal outcomes. Expert Opin Drug Deliv. 2017;14(8):973-82. [Crossref]  [PubMed] 
  14. Pecho OE, Ghinea R, Alessandretti R, Pérez MM, Della Bona A. Visual and instrumental shade matching using CIELAB and CIEDE2000 color difference formulas. Dent Mater. 2016;32(1):82-92. [Crossref]  [PubMed] 
  15. Ulusoy NB, Arikan V, Akbay Oba A. Effect of mouthwashes on the discolouration of restorative materials commonly used in paediatric dentistry. Eur Arch Paediatr Dent. 2018;19(3):147-53. [Crossref]  [PubMed] 
  16. Ceci M, Rattalino D, Viola M, Beltrami R, Chiesa M, Colombo M, et al. Resin infiltrant for non-cavitated caries lesions: evaluation of color stability. J Clin Exp Dent. 2017;9(2):e231-e7. [PubMed]  [PMC] 
  17. Rey N, Benbachir N, Bortolotto T, Krejci I. Evaluation of the staining potential of a caries infiltrant in comparison to other products. Dent Mater J. 2014;33(1):86-91. [Crossref]  [PubMed] 
  18. de Abreu JLB, Sampaio CS, Benalcázar Jalkh EB, Hirata R. Analysis of the color matching of universal resin composites in anterior restorations. J Esthet Restor Dent. 2021;33(2):269-76. [Crossref]  [PubMed] 
  19. Alpkilic DS, Ongul D, Isler Deger S. Stainability of different ceramic materials against mouth rinses and effect of polishing after staining. J Prosthet Dent. 2021;126(5):686.e1-6.e7. [Crossref]  [PubMed] 
  20. Al-Samadani KH. The effect of preventive agents (mouthwashes/gels) on the color stability of dental resin-based composite materials. Dent J (Basel). 2017;5(2):18. [Crossref]  [PubMed]  [PMC] 
  21. Araújo GS, Naufel FS, Alonso RC, Lima DA, Puppin-Rontani RM. Influence of Staining Solution and Bleaching on Color Stability of Resin Used for Caries Infiltration. Oper Dent. 2015;40(6):E250-6. [Crossref]  [PubMed] 
  22. Gómez-Polo C, Portillo Muñoz M, Lorenzo Luengo MC, Vicente P, Galindo P, Martín Casado AM. Comparison of the CIELab and CIEDE2000 color difference formulas. J Prosthet Dent. 2016;115(1):65-70. [Crossref]  [PubMed] 
  23. T Celik AC, Coban E, Ulker HE. Effects of mouthwashes on color stability and surface roughness of three different resin-based composites. Niger J Clin Pract. 2021;24(4):555-60. [Crossref]  [PubMed] 
  24. Gürgan S, Onen A, Köprülü H. In vitro effects of alcohol-containing and alcohol-free mouthrinses on microhardness of some restorative materials. J Oral Rehabil. 1997;24(3):244-6. [Crossref]  [PubMed] 
  25. Basrani B, Lemonie C. Chlorhexidine gluconate. Aust Endod J. 2005;31(2):48-52. [Crossref]  [PubMed] 
  26. Lamba B, Lamba A, Ponnappa K. Effect of mouth rinses on the color of three tooth-colored restorative materials. ISOM. 2012;5(3):104-9. [Crossref] 
  27. Zanatta FB, Antoniazzi RP, Rösing CK. Staining and calculus formation after 0.12% chlorhexidine rinses in plaque-free and plaque covered surfaces: a randomized trial. J Appl Oral Sci. 2010;18(5):515-21. [Crossref]  [PubMed]  [PMC] 
  28. ElEmbaby Ael-S. The effects of mouth rinses on the color stability of resin-based restorative materials. J Esthet Restor Dent. 2014;26(4):264-71. [Crossref]  [PubMed] 
  29. Villalta P, Lu H, Okte Z, Garcia-Godoy F, Powers JM. Effects of staining and bleaching on color change of dental composite resins. J Prosthet Dent. 2006;95(2):137-42. [Crossref]  [PubMed] 
  30. Trauth KG, Godoi AP, Colucci V, Corona SA, Catirse AB. The influence of mouthrinses and simulated toothbrushing on the surface roughness of a nanofilled composite resin. Braz Oral Res. 2012;26(3):209-14. [Crossref]  [PubMed] 
  31. Jervøe-Storm PM, Schulze H, Jepsen S. A randomized cross-over short-term study on the short-term effects of a zinc-lactate containing mouthwash against oral malodour. J Breath Res. 2019;13(2):026005. [Crossref]  [PubMed] 
  32. Paraskevas S, Danser MM, Timmerman MF, Van der Velden U, Van der Weijden GA. Effect of a combination of amine/stannous fluoride dentifrice and mouthrinse in periodontal maintenance patients. J Clin Periodontol. 2004;31(3):177-83. [Crossref]  [PubMed] 
  33. Van Loveren C. Antimicrobial activity of fluoride and its in vivo importance: identification of research questions. Caries Res. 2001;35 Suppl 1:65-70. [Crossref]  [PubMed] 
  34. Brecx M, Netuschil L, Reichert B, Schreil G. Efficacy of Listerine, Meridol and chlorhexidine mouthrinses on plaque, gingivitis and plaque bacteria vitality. J Clin Periodontol. 1990;17(5):292-7. [Crossref]  [PubMed] 
  35. Falkensammer F, Arnetzl GV, Wildburger A, Freudenthaler J. Color stability of different composite resin materials. J Prosthet Dent. 2013;109(6):378-83. [Crossref]  [PubMed] 

.: Up To Date

Login



Contact


Ortadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş.

.: Address

Turkocagi Caddesi No:30 06520 Balgat / ANKARA
Phone: +90 312 286 56 56
Fax: +90 312 220 04 70
E-mail: info@turkiyeklinikleri.com

.: Manuscript Editing Department

Phone: +90 312 286 56 56/ 2
E-mail: yaziisleri@turkiyeklinikleri.com

.: English Language Redaction

Phone: +90 312 286 56 56/ 145
E-mail: tkyayindestek@turkiyeklinikleri.com

.: Marketing Sales-Project Department

Phone: +90 312 286 56 56/ 142
E-mail: reklam@turkiyeklinikleri.com

.: Subscription and Public Relations Department

Phone: +90 312 286 56 56/ 118
E-mail: abone@turkiyeklinikleri.com

.: Customer Services

Phone: +90 312 286 56 56/ 118
E-mail: satisdestek@turkiyeklinikleri.com

1. TERMS OF USE

1.1. To use the web pages with http://www.turkiyeklinikleri.com domain name or the websites reached through the sub domain names attached to the domain name (They will be collectively referred as "SITE"), please read the conditions below. If you do not accept these terms, please cease to use the "SITE." "SITE" owner reserves the right to change the information on the website, forms, contents, the "SITE," "SITE" terms of use anytime they want.

1.2. The owner of the "SITE" is Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. (From now on it is going to be referred as "Turkiye Klinikleri", shortly) and it resides at Turkocagi cad. No:30, 06520 Balgat Ankara. The services in the "SITE" are provided by "Turkiye Klinikleri."

1.3. Anyone accessing the "SITE" with or without a fee whether they are a natural person or a legal identity is considered to agree these terms of use. In this contract hereby, "Turkiye Klinikleri" may change the stated terms anytime. These changes will be published in the "SITE" periodically and they will be valid when they are published. Any natural person or legal identity benefiting from and reaching to the "SITE" are considered to be agreed to any change on hereby contract terms done by "Turkiye Klinikleri."

1.4. The "Terms of Use" hereby is published in the website with the last change on March 30th 2014 and the "SITE" is activated by enabling the access to everyone. The "Terms of Use" hereby is also a part of the any "USER Contract" was and/or will be done with the users using "Turkiye Klinikleri" services with or without a fee an inseparable.

2. DEFINITIONS

2.1. "SITE": A website offering different kind of services and context with a certain frame determined by "Turkiye Klinikleri" and it is accessible on-line on http://www.turkiyeklinikleri.com domain name and/or subdomains connected to the domain name.

2.2. USER: A natural person or a legal identity accessing to the "SITE" through online settings.

2.3. LINK: A link enabling to access to another website through the "SITE", the files, the context or through another website to the "SITE", the files and the context.

2.4. CONTEXT: Any visual, literary and auditory images published in the "Turkiye Klinikleri", "SITE" and/or any website or any accessible information, file, picture, number/figures, price, etc.

2.5. "USER CONTRACT": An electronically signed contract between a natural or a legal identity benefiting from special services "Turkiye Klinikleri" will provide and "Turkiye Klinikleri".

3. SCOPE OF THE SERVICES

3.1. "Turkiye Klinikleri" is completely free to determine the scope and quality of the services via the "SITE".

3.2. To benefit the services of "Turkiye Klinikleri" "SITE", the "USER" must deliver the features that will be specified by "Turkiye Klinikleri". "Turkiye Klinikleri" may change this necessity any time single-sided.

3.3. Not for a limited number, the services "Turkiye Klinikleri" will provide through the "SITE" for a certain price or for free are;

- Providing scientific articles, books and informative publications for health industry.

- Providing structural, statistical and editorial support to article preparation stage for scientific journals.

4. GENERAL PROVISIONS

4.1. "Turkiye Klinikleri" is completely free to determine which of the services and contents provided in the "SITE" will be charged.

4.2. People benefiting from the services provided by "Turkiye Klinikleri" and using the website can use the "SITE" only according to the law and only for personal reasons. Users have the criminal and civil liability for every process and action they take in the "SITE". Every USER agrees, declares and undertakes that they will not proceed by any function or action infringement of rights of "Turkiye Klinikleri"s and/or other third parties', they are the exclusive right holder on usage, processing, storage, made public and revealing any written, visual or auditory information reported to Turkiye Klinikleri" and/or "SITE" to the third parties. "USER" agrees and undertakes that s/he will not duplicate, copy, distribute, process, the pictures, text, visual and auditory images, video clips, files, databases, catalogs and lists within the "SITE", s/he will not be using these actions or with other ways to compete with "Turkiye Klinikleri", directly or indirectly.

4.3. The services provided and the context published within the "SITE" by third parties is not under the responsibility of "Turkiye Klinikleri", institutions collaborated with "Turkiye Klinikleri", "Turkiye Klinikleri" employee and directors, "Turkiye Klinikleri" authorized salespeople. Commitment to accuracy and legality of the published information, context, visual and auditory images provided by any third party are under the full responsibility of the third party. "Turkiye Klinikleri" does not promise and guarantee the safety, accuracy and legality of the services and context provided by a third party.

4.4. "USER"s cannot act against "Turkiye Klinikleri", other "USER"s and third parties by using the "SITE". "Turkiye Klinikleri" has no direct and/or indirect responsibility for any damage a third party suffered or will suffer regarding "USER"s actions on the "SITE" against the rules of the hereby "Terms of Use" and the law.

4.5. "USER"s accept and undertake that the information and context they provided to the "SITE" are accurate and legal. "Turkiye Klinikleri" is not liable and responsible for promising and guaranteeing the verification of the information and context transmitted to "Turkiye Klinikleri" by the "USER"s, or uploaded, changed and provided through the "SITE" by them and whether these information are safe, accurate and legal.

4.6. "USER"s agree and undertake that they will not perform any action leading to unfair competition, weakening the personal and commercial credit of "Turkiye Klinikleri" and a third party,  encroaching and attacking on personal rights within the "SITE" in accordance with the Turkish Commercial Code Law.

4.7. "Turkiye Klinikleri" reserves the right to change the services and the context within the "SITE"  anytime. "Turkiye Klinikleri" may use this right without any notification and timelessly. "USER"s have to make the changes and/or corrections "Turkiye Klinikleri" required immediately. Any changes and/or corrections that are required by "Turkiye Klinikleri", may be made by "Turkiye Klinikleri" when needed. Any harm, criminal and civil liability resulted or will result from changes and/or corrections required by "Turkiye Klinikleri" and were not made on time by the "USER"s belongs completely to the users.

4.8. "Turkiye Klinikleri" may give links through the "SITE" to other websites and/or "CONTEXT"s and/or folders that are outside of their control and owned and run by third parties. These links are provided for ease of reference only and do not hold qualification for support the respective web SITE or the admin or declaration or guarantee for the information inside. "Turkiye Klinikleri" does not hold any responsibility over the web-sites connected through the links on the "SITE", folders and context, the services or products on the websites provided through these links or their context.

4.9. "Turkiye Klinikleri" may use the information provided to them by the "USERS" through the "SITE" in line with the terms of the "PRIVACY POLICY" and "USER CONTRACT". It may process the information or classify and save them on a database. "Turkiye Klinikleri" may also use the USER's or visitor's identity, address, e-mail address, phone number, IP number, which sections of the "SITE" they visited, domain type, browser type, date and time information to provide statistical evaluation and customized services.

5. PROPRIETARY RIGHTS

5.1. The information accessed through this "SITE" or provided by the users legally and all the elements (including but not limited to design, text, image, html code and other codes) of the "SITE" (all of them will be called as studies tied to "Turkiye Klinikleri"s copyrights) belongs to "Turkiye Klinikleri". Users do not have the right to resell, process, share, distribute, display or give someone permission to access or to use the "Turkiye Klinikleri" services, "Turkiye Klinikleri" information and the products under copyright protection by "Turkiye Klinikleri". Within hereby "Terms of Use" unless explicitly permitted by "Turkiye Klinikleri" nobody can reproduce, process, distribute or produce or prepare any study from those under "Turkiye Klinikleri" copyright protection.

5.2. Within hereby "Terms of Use", "Turkiye Klinikleri" reserves the rights for "Turkiye Klinikleri" services, "Turkiye Klinikleri" information, the products associated with "Turkiye Klinikleri" copyrights, "Turkiye Klinikleri" trademarks, "Turkiye Klinikleri" trade looks or its all rights for other entity and information it has through this website unless it is explicitly authorized by "Turkiye Klinikleri".

6. CHANGES IN THE TERMS OF USE

"Turkiye Klinikleri" in its sole discretion may change the hereby "Terms of Use" anytime announcing within the "SITE". The changed terms of the hereby "Terms of Use" will become valid when they are announced. Hereby "Terms of Use" cannot be changed by unilateral declarations of users.

7. FORCE MAJEURE

"Turkiye Klinikleri" is not responsible for executing late or never of this hereby "Terms of Use", privacy policy and "USER Contract" in any situation legally taken into account as force majeure. Being late or failure of performance or non-defaulting of this and similar cases like this will not be the case from the viewpoint of "Turkiye Klinikleri", and "Turkiye Klinikleri" will not have any damage liability for these situations. "Force majeure" term will be regarded as outside of the concerned party's reasonable control and any situation that "Turkiye Klinikleri" cannot prevent even though it shows due diligence. Also, force majeure situations include but not limited to natural disasters, rebellion, war, strike, communication problems, infrastructure and internet failure, power cut and bad weather conditions.

8. LAW AND AUTHORISATION TO FOLLOW

Turkish Law will be applied in practicing, interpreting the hereby "Terms of Use" and managing the emerging legal relationships within this "Terms of Use" in case of finding element of foreignness, except for the rules of Turkish conflict of laws. Ankara Courts and Enforcement Offices are entitled in any controversy happened or may happen due to hereby contract.

9. CLOSING AND AGREEMENT

Hereby "Terms of Use" come into force when announced in the "SITE" by "Turkiye Klinikleri". The users are regarded to agree to hereby contract terms by using the "SITE". "Turkiye Klinikleri" may change the contract terms and the changes will be come into force by specifying the version number and the date of change on time it is published in the "SITE".

 

30.03.2014

Privacy Policy

We recommend you to read the terms of use below before you visit our website. In case you agree these terms, following our rules will be to your favor. Please read our Terms of Use thoroughly.

www.turkiyeklinikleri.com website belongs to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. and is designed in order to inform physicians in the field of health

www.turkiyeklinikleri.com cannot reach to user’s identity, address, service providers or other information. The users may send this information to the website through forms if they would like to. However, www.turkiyeklinikleri.com may collect your hardware and software information. The information consists of your IP address, browser type, operating system, domain name, access time, and related websites. www.turkiyeklinikleri.com cannot sell the provided user information (your name, e-mail address, home and work address, phone number) to the third parties, publish it publicly, or keep it in the website. Gathered information has a directing feature to be a source for the website’s visitor profile, reporting and promotion of the services.

www.turkiyeklinikleri.com uses the taken information:

-To enhance, improve and maintain the quality of the website

-To generate visitor’s profile and statistical data

-To determine the tendency of the visitors on using our website

-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

info@turkiyeklinikleri.com