Turkiye Klinikleri Journal of Medical Sciences

.: ORIGINAL RESEARCH
Bir Üniversite Hastanesinin Dermatoloji Polikliniğine Başvuran Hidradenitis Süpürativa Hastalarının Demografik ve Klinik Özellikleri: Prospektif Bir Çalışma
Clinical and Demographic Characteristics of Hidradenitis Suppurativa Patients Application to the Dermatology Clinic of a University Hospital: A Prospective Study
Bilal SULAa , Ümit EKİNCİa
aDicle Üniversitesi Tıp Fakültesi Hastanesi, Deri ve Zührevi Hastalıkları ABD, Diyarbakır, Türkiye
Turkiye Klinikleri J Med Sci. 2023;43(2):171-7
doi: 10.5336/medsci.2022-93830
Article Language: TR
Full Text
ÖZET
Amaç: Hidradenitis süpürativa (HS) veya akne inversa, çoğunlukla puberte sonrası ortaya çıkan ağrılı, derin yerleşimli, iltihaplı lezyonlarla karakterize kronik, inflamatuar, tekrarlayıcı bir deri hastalığıdır. Aksiller, inguinal ve anogenital bölgeler gibi vücudun apokrin bezlerden zengin bölgelerinde daha sık görülür. Çalışmamızda, dermatoloji polikliniğine başvuran HS tanılı ve ilk defa HS tanısı alan hastaların klinik ve sosyodemografik özelliklerini değerlendirdik. Gereç ve Yöntemler: Çalışmaya, dermatoloji ana bilim dalı polikliniğine başvuran HS tanılı ve ilk defa HS tanısı alan 50 hasta dâhil edildi. Çalışmaya dâhil edilen hastaların sosyodemografik özellikleri ve klinik bulguları kaydedildi. HS tanı kriterlerini karşılayan tüm hastalar çalışmaya dâhil edildi. Bulgular: HS ortalama başlangıç yaşı 22,52 yıl olup, erkeklerde daha ileri yaşlardaydı (p=0,001). HS tanısında ortalama gecikme süresi 73,66 ay olup, erkeklerde daha kısaydı (p=0,003). Hastaların %68'i fazla kilolu, obez ve morbid obez kategorisindeydi. Hastaların %72'sinde sigara öyküsü vardı. Hasta yoğunluğu orta ve şiddetli Hurley evrelerinde daha fazlaydı (evre II %48 ve evre III %32). En sık aksiller bölge (%90), inguinal bölge (%70) ve meme arası-altı bölgesi (%46) etkilenmişti. Erkeklerde aksiller ve atipik yerleşim bölgeleri, kadınlarda ise meme arası ve altı bölgesi yerleşimi anlamlıydı (p<0,05). Sigara öyküsü, yerleşim yerinin aksiller, inguinal ve gluteal bölge olması, toplam etkilenen bölge sayısı, foliküler oklüzyon bileşenlerinin eşlik etmesi ile hastalık şiddeti ilişkiliydi (p<0,05). Sonuç: Çalışmamızda hasta sayısı sınırlı olsa da ülkemiz HS epidemiyolojisine de katkıda bulunacaktır. Elde ettiğimiz veriler; ülkemiz ve diğer ülke verilerine benzemekle beraber birtakım farklılıklar göstermektedir. Bu da HS etiyopatogenezinde genetik ve etnik faktörlerin, sigara ve beslenme alışkanlıklarının rolü olabileceğini düşündürmektedir.

Anahtar Kelimeler: Epidemiyoloji; hidradenitis süpürativa; Hurley evrelemesi; klinik özellikler; sosyodemografik özellikler
ABSTRACT
Objective: Hidradenitis suppurativa (HS) or acne inversa is a chronic, inflammatory, recurrent skin disease characterized by painful, deeply located, inflammatory lesions that occur mostly after puberty. It is more common in areas of the body rich in apocrine glands, such as the axilla, inguinal and anogenital regions. In our study, we evaluated the clinical and sociodemographic characteristics of patients diagnosed with HS and diagnosed with HS for the first time, who applied to the dermatology policlinic. Material and Methods: Fifty patients diagnosed with HS and diagnosed with HS for the first time, who applied to the dermatology department polyclinic were included in the study. Sociodemographic characteristics and clinical findings of the patients included in the study were recorded. All patients who met the diagnostic criteria for HS were included in the study. Results: The mean age of onset of HS was 22.52 years and it was more advanced in males (p=0.001). The mean delay time in the diagnosis of HS was 73.66 months and it was shorter in men (p=0.003). 68% of the patients were in the overweight, obese and morbidly obese categories. 72% of the patients had a history of smoking. In our study, the patient density was higher in moderate and severe Hurley stages (Hurley stage II 48% and stage III 32%). The axillary region (90%) and inguinal region (70%) and interbreast and submammary region (46%) were most frequently affected. In men, axillary and atypical localization regions were significant, while in women, the location between and below the breasts was significant (p<0.05). The severity of the disease was associated with smoking history, localization in the axilla, inguinal and gulteal region, total number of affected areas, and accompanying follicular occlusion components (p<0.05). Conclusion: Although the number of patients in our study was limited, it will also contribute to the epidemiology of HS in our country. The data we obtained; although it is similar to the data of our country and other countries, it shows some differences. This suggests that genetic and ethnic factors, smoking and dietary habits may play a role in the etiopathogenesis of HS.

Keywords: Epidemiology; hidradenitis suppurativa; Hurley staging; clinical features; sociodemographic features
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