Turkiye Klinikleri Journal of Ophthalmology

.: CASE REPORTS
Çocukluk Çağı Fundus Tümörlerinin Ayırıcı Tanısında Retina ve Retina Pigment Epitelinin Kombine Hamartomu
Combined Hamartoma of the Retina and Retinal Pigment Epithelium in the Differential Diagnosis of Fundus Tumors in Children
Gülsüm GENÇa, A. Kaan GÜNDÜZa , Levent KARABAŞb
aAnkara Üniversitesi Tıp Fakültesi, Göz Hastalıkları ABD, Ankara, TÜRKİYE
bKocaeli Üniversitesi Tıp Fakültesi, Göz Hastalıkları ABD, Kocaeli, TÜRKİYE
Turkiye Klinikleri J Ophthalmol. 2020;29(4):333-8
doi: 10.5336/ophthal.2020-75953
Article Language: TR
Full Text
ÖZET
 Dokuz yaşındaki kız hasta, sol gözde görme azlığı ve dışa kayma nedeni ile muayene edildi. Görme ışık hissi idi. Ön segment muayenesi normal idi. Funduskopide, makulada klinik olarak retina ve retina pigment epitelinin kombine hamartomu ile uyumlu amelanotik bir kitle mevcuttu. Lezyon B-mod ultrasonografide akustik gölgelenme ve düzensiz sınır gösterdi. Retina ve retina pigment epitelinin kombine hamartomu; fundus otofloresan incelemede izootofloresan, fluorosein anjiyografide erken ve geç fazda izofloresan gösterdi. Retina pigment epitel hiperplazisi görülen bölgeler otofloresan görüntülemede hipootofloresan ve fluorosein anjiyografide hipofloresan idi. Lezyon EDI (enhanced depht imaging) optik koherens tomografide (EDI-OKT) difüz retinal kalınlaşma, retina pigment epitel hiperplazisine bağlı gölgelenme ve fokal vitreoretinal traksiyon gösterdi. Retina ve retina pigment epitelinin kombine hamartomu, nadir görülen benign bir retina lezyonudur. Retinoblastom ile karışabilir. Bu çalışmada, retina ve retina pigment epitelinin kombine hamartomu tanısı konan bir olgunun klinik ve multimodal görüntüleme özellikleri sunulmaktadır.

Anahtar Kelimeler: Hamartom; retina ve retina pigment epiteli; retina; optik koherens tomografi (OKT); fluorosein anjiyografi; ultrasonografi
ABSTRACT
 T A 9 years old girl was examined because of low vision and exotropia in the left eye. Vision was light perception. Anterior segment examination was normal. Funduscopically, there was an amelanotic mass in the macula diagnosed clinically as combined hamartoma of the retina and retinal pigment epitelium. Areas of retinal pigment epitel hyperplasia demonstrated hypoautofluorescence on autoflorescence imaging and hypofluorescence on fluorescein angiography. The lesion demonstrated acoustic hollowness and irreguler borders on B-mode ultrasonography. Combined hamartoma of the retina and retina pigment epithelium showed isoautoflorescence on fundus autoflorescence imaging, and early and late isofluorescence on fluorescein angiography. The lesion demonstrated diffuse retinal thickening, shadowing from retinal pigment epithelial hyperplasia and focal vitreoretinal traction on enhanced depht imaging optic coherence tomography (EDI-OCT). Combined hamartoma of the retina and retina pigment epithelium is a rare benign retinal lesion. It may be misdiagnosed as retinoblastoma. In this study, we present the clinical and multimodal imaging findings of a case diagnosed with combined hamartoma retina and retina pigment epithelium.

Keywords: Hamartoma; retina and retina pigment epithelium; retina; optical coherence tomography (OCT); fluorescein anjiography; ultrasonography
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