Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Comparison of Chronological Age and Estimated Age Obtained by Using Hand-Wrist and Panoramic Radiographic Data with Different Age Estimation Methods: A Cross-Sectional Study
El-Bilek ve Panoramik Radyografik Verilerle Farklı Yaş Tayini Metotları Kullanılarak Elde Edilen Tahmini Yaşın Kronolojik Yaşla Karşılaştırılması: Kesitsel Çalışma
Tuğçe Nur ŞAHİNa , İzzet YAVUZb
aDepartment of Pediatric Dentistry, Karamanoğlu Mehmetbey University Ahmet Keleşoğlu Faculty of Dentistry, Karaman, Türkiye
bDepartment of Pediatric Dentistry, Harran University Faculty of Dentistry, Şanlıurfa, Türkiye
Turkiye Klinikleri J Dental Sci. 2024;30(1):74-82
doi: 10.5336/dentalsci.2023-99153
Article Language: EN
Full Text
ABSTRACT
Objective: The aim of the study is to compare the alignment of estimated ages (EA) obtained using the Cameriere open apices method (COAM), Demirjian method (DM), Greulich & Pyle Atlas method (GPAM), and Cameriere hand-wrist method (CHWM) with the chronological ages (CA) of cases and determine which method provides the closest result to CA in the most practical way. Material and Methods: Orthopantomography and wrist X-rays of 287 cases aged 9- 14 years were used. The difference between CA and EA obtained by COAM, CHWM, DM and GPAM methods and dental age (DA), bone age (BA) were evaluated. We employed Shapiro-Wilk's, KolmogorovSmirnov, Mann-Whitney U, Kruskal-Wallis H, and Wilcoxon tests, along with the Kappa coefficient, considering p<0.05 as significant. Results: In males, the CA-EA difference was found to be underestimated by 0.74 and 0.01 years for COAM and GPAM, and overestimated by 0.65 and 0.32 years for DM and CHWM, respectively. In females, this difference was underestimated by 0.61 years for COAM and overestimated by 0.64, 0.85, and 0.43 years for DM, CHWM, and GPAM, respectively (p<0.005). Conclusion: GPAM was found to be the closest to CA and the most practical method. When determining age, it's crucial to consider both DA and BA together. Using the evaluated methods for age estimation after necessary modifications are made seems appropriate.

Keywords: Age determination by teeth; age determination by skeleton; tooth; bone development
ÖZET
Amaç: Çalışmanın amacı, Cameriere açık apeks yöntemi [Cameriere open apices method (COAM)], Demirjian yöntemi [Demirjian method (DM)], Greulich & Pyle Atlas yöntemi [Greulich & Pyle Atlas method (GPAM)] ve Cameriere el-bilek yöntemi [Cameriere handwrist method (CHWM)] kullanılarak elde edilen tahmini yaşların [estimated ages (EA)] vakaların kronolojik yaşları [chronological ages (CA)] ile karşılaştırılmasıyla hangi yöntemin CA'ya en yakın sonucu en pratik şekilde sağladığını tespit etmektir. Gereç ve Yöntemler: Çalışmada yaşları 9-14 arasında değişen 287 olgunun ortopantomografisi ve el-bilek röntgeni kullanıldı. CA ile COAM, CHWM, DM ve GPAM kullanılarak elde edilen EA ve CA ile diş yaşı [dental age (DA)] ve kemik yaşı [bone age (BA)] farkları değerlendirildi. p<0,05'i anlamlı kabul ederek Shapiro-Wilk, Kolmogorov-Smirnov, Mann-Whitney U, Kruskal-Wallis H ve Wilcoxon testleri ve Kappa katsayısı istatistiksel değerlendirme amacıyla kullanıldı. Bulgular: Erkeklerde CA-EA farkının COAM ve GPAM için 0,74 ve 0,01 yıl eksik tahmin edildiği, DM ve CHWM için ise sırasıyla 0,65 ve 0,32 yıl fazla tahmin edildiği görüldü. Kadınlarda bu fark COAM için 0,61 yıl eksik, DM, CHWM ve GPAM için ise sırasıyla 0,64, 0,85 ve 0,43 yıl fazla tahmin edilmiştir (p<0,005). Sonuç: GPAM'nin CA'ya en yakın sonucu veren, en pratik yöntem olduğu görüldü. Yaşı belirlerken hem DA hem de BA'yı birlikte düşünmek oldukça önemlidir. Çalışmada incelenmiş olan yöntemlerin gerekli modifikasyonlar yapıldıktan sonra yaş tahmini için kullanılmasının daha uygun olacağı düşünülmektedir.

Anahtar Kelimeler: Dişlerden yaş tayini; iskeletten yaş tayini; diş; kemik gelişimi
REFERENCES:
  1. Varkkola O, Ranta H, Metsäniitty M, Sajantila A. Age assessment by the Greulich and Pyle method compared to other skeletal X-ray and dental methods in data from Finnish child victims of the Southeast Asian Tsunami. Forensic Sci Med Pathol. 2011;7(4):311-6. [Crossref]  [PubMed] 
  2. Meinl A. The application of dental age estimation methods: comparative validity and problems in practical implementation [Doctoral thesis]. Vienna: University of Vienna; 2007. Erişim tarihi: 20/07/2023 [Link] 
  3. Panchbhai AS. Dental radiographic indicators, a key to age estimation. Dentomaxillofac Radiol. 2011;40(4):199-212. [Crossref]  [PubMed]  [PMC] 
  4. Demirkıran DS, Çelikel A, Zeren C, Arslan MM. Yaş tespitinde kullanılan yöntemler [Methods for age estimation]. Dicle Medical Journal. 2014;41(1):238-43. [Crossref] 
  5. Edeiken J, Hodes P. Reticuloendothelioses. Roentgen Diagnosis of Diseases of Bone. 1st ed. Baltimore: Williams & Wilkins; 1967. p.292-6.
  6. Çöloğlu AS. Kemik ve diş gelişimini etkileyen faktörler: yaş tayini çalışmalarındaki önemi [The factors affecting the development of bones and teeth, and importance in age determination]. Journal of Forensic Medicine. 1987;3(1-4):117-22. [Link] 
  7. Isır AB. Adli hekimlikte yaş tayini. Koç S, Can M, editörler. Birinci Basamakta Adli Tıp. 2. Baskı. İstanbul: İstanbul Tabip Odası; 2009. p.222-31.
  8. Schmeling A, Grundmann C, Fuhrmann A, Kaatsch HJ, Knell B, Ramsthaler F, et al. Criteria for age estimation in living individuals. Int J Legal Med. 2008;122(6):457-60. [Crossref]  [PubMed] 
  9. Demirjian A, Goldstein H, Tanner JM. A new system of dental age assessment. Hum Biol. 1973;45(2):211-27. [PubMed] 
  10. Turhal RI, Önem E, Tuğsel Z. Ege Bölgesinde yaşayan çocuklarin yaş tayininde Williems ve Demirjian yöntemlerinin karşılaştırılması [Comparison of Willems and Demirjian methods for age estimation in a pediatric Aegean Population]. Ege Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2021;42(3):199-204. [Crossref] 
  11. Cameriere R, Ferrante L, Cingolani M. Age estimation in children by measurement of open apices in teeth. Int J Legal Med. 2006;120(1):49-52. [Crossref]  [PubMed] 
  12. Cameriere R, Ferrante L, Mirtella D, Cingolani M. Carpals and epiphyses of radius and ulna as age indicators. Int J Legal Med. 2006;120(3):143-6. [Crossref]  [PubMed] 
  13. Cameriere R, Bestetti F, Velandia Palacio LA, Riccomi G, Skrami E, Parente V, et al. Carpals and epiphyses of radius and ulna as age indicators using longitudinal data: a Bayesian approach. Int J Legal Med. 2019;133(1):197-204. [Crossref]  [PubMed] 
  14. Greulich W, Pyle S. Radiographic Atlas of Skeletal Development of the Hand and Wrist. 2nd ed. Stanford, Calif: Stanford Univ. Press; 1959. [Crossref] 
  15. Acungil İ. Yaş tayininde el-bilek rayografilerinin geçerlilik ve değerliliği ile ilgili kör bir çalışma [Uzmanlık tezi]. Ankara: Ankara Üniversitesi; 2014. Erişim tarihi: 23/07/2023 [Link] 
  16. Apaydin BK, Yasar F. Accuracy of the demirjian, willems and cameriere methods of estimating dental age on turkish children. Niger J Clin Pract. 2018;21(3):257-63. [Crossref]  [PubMed] 
  17. Tunc ES, Koyuturk AE. Dental age assessment using Demirjian's method on northern Turkish children. Forensic Sci Int. 2008;175(1):23-6. [Crossref]  [PubMed] 
  18. Miloglu O, Celikoglu M, Dane A, Cantekin K, Yilmaz AB. Is the assessment of dental age by the Nolla method valid for eastern Turkish children? J Forensic Sci. 2011;56(4):1025-8. [Crossref]  [PubMed] 
  19. Özer K. Büyüme ve gelişme sürecinde egzersiz [Exercise during growth and development]. Journal of Physical Education and Sports Studies. 1990;1(1):30-2. [Link] 
  20. Santoro V, Roca R, De Donno A, Fiandaca C, Pinto G, Tafuri S, et al. Applicability of Greulich and Pyle and Demirijan aging methods to a sample of Italian population. Forensic Sci Int. 2012;221(1-3):153.e1-5. [Crossref]  [PubMed] 
  21. Çarıkçıoğlu B, Değirmenci A. Accuracy of the radiographic methods of Willems, Cameriere and Blenkin-Evans on age estimation for Turkish children in the northwest Anatolia region. Australian Journal of Forensic Sciences. 2023;55(2):156-67. [Crossref] 
  22. Ozveren N, Serindere G, Meric P, Cameriere R. A comparison of the accuracy of Willems' and Cameriere's methods based on panoramic radiography. Forensic Sci Int. 2019;302:109912. [Crossref]  [PubMed] 
  23. Krailassiri S, Anuwongnukroh N, Dechkunakorn S. Relationships between dental calcification stages and skeletal maturity indicators in Thai individuals. Angle Orthod. 2002;72(2):155-66. [PubMed] 
  24. Patel PS, Chaudhary AR, Dudhia BB, Bhatia PV, Soni NC, Jani YV. Accuracy of two dental and one skeletal age estimation methods in 6-16 year old Gujarati children. J Forensic Dent Sci. 2015;7(1):18-27. [Crossref]  [PubMed]  [PMC] 
  25. Büken B, Erzengin OU, Büken E, Safak AA, Yazici B, Erkol Z. Comparison of the three age estimation methods: which is more reliable for Turkish children? Forensic Sci Int. 2009;183(1-3):103.e1-7. [Crossref]  [PubMed] 
  26. Büken B, Safak AA, Yazici B, Büken E, Mayda AS. Is the assessment of bone age by the Greulich-Pyle method reliable at forensic age estimation for Turkish children? Forensic Sci Int. 2007;173(2-3):146-53. [Crossref]  [PubMed] 
  27. Büken B, Büken E, Şafak AA, Yazici B, Erkol Z, Mayda AS. Is the Gök Atlas sufficiently reliable for forensic age determination of Turkish children? Turkish Journal of Medical Sciences. 2008;38(4):319-27. [Link] 
  28. Alshamrani K, Messina F, Offiah AC. Is the Greulich and Pyle atlas applicable to all ethnicities? A systematic review and meta-analysis. Eur Radiol. 2019;29(6):2910-23. [Crossref]  [PubMed]  [PMC] 
  29. De Luca S, Mangiulli T, Merelli V, Conforti F, Velandia Palacio LA, Agostini S, et al. A new formula for assessing skeletal age in growing infants and children by measuring carpals and epiphyses of radio and ulna. J Forensic Leg Med. 2016;39:109-16. [Crossref]  [PubMed] 
  30. Özdemir Tosyalıoğlu FE, Özgür B, Çehreli SB, Arrais Ribeiro IL, Cameriere R. The accuracy of Cameriere methods in Turkish children: chronological age estimation using developing teeth and carpals and epiphyses of the ulna and radius. Forensic Sci Med Pathol. 2023;19(3):372-81. [Crossref]  [PubMed] 
  31. Kanbur NO, Kanli A, Derman O, Eifan A, Ataç A. The relationships between dental age, chronological age and bone age in Turkish adolescents with constitutional delay of growth. J Pediatr Endocrinol Metab. 2006;19(8):979-85. [Crossref]  [PubMed] 
  32. Kumar V, Hegde SK, Bhat SS. The relationship between dental age, bone age and chronological age in children with short stature. International Journal of Contemporary Dentistry 2011;2(4):6-11. [Link] 
  33. Yaşar ZF, Büken E, Tekindal MA. Demirjian metodu farklı ülkelerde yaş tayininde kullanilabilir mi? [Could demirjian's method be used in age determination in different countries?]. Adli Tıp Bülteni. 2016;21(3):144-52. [Crossref] 
  34. Cameriere R, De Luca S, Biagi R, Cingolani M, Farronato G, Ferrante L. Accuracy of three age estimation methods in children by measurements of developing teeth and carpals and epiphyses of the ulna and radius. J Forensic Sci. 2012;57(5):1263-70. [Crossref]  [PubMed] 
  35. Willems G. A review of the most commonly used dental age estimation techniques. J Forensic Odontostomatol. 2001;19(1):9-17. [PubMed] 

.: Up To Date

Login



Contact


Ortadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş.

.: Address

Turkocagi Caddesi No:30 06520 Balgat / ANKARA
Phone: +90 312 286 56 56
Fax: +90 312 220 04 70
E-mail: info@turkiyeklinikleri.com

.: Manuscript Editing Department

Phone: +90 312 286 56 56/ 2
E-mail: yaziisleri@turkiyeklinikleri.com

.: English Language Redaction

Phone: +90 312 286 56 56/ 145
E-mail: tkyayindestek@turkiyeklinikleri.com

.: Marketing Sales-Project Department

Phone: +90 312 286 56 56/ 142
E-mail: reklam@turkiyeklinikleri.com

.: Subscription and Public Relations Department

Phone: +90 312 286 56 56/ 118
E-mail: abone@turkiyeklinikleri.com

.: Customer Services

Phone: +90 312 286 56 56/ 118
E-mail: satisdestek@turkiyeklinikleri.com

1. TERMS OF USE

1.1. To use the web pages with http://www.turkiyeklinikleri.com domain name or the websites reached through the sub domain names attached to the domain name (They will be collectively referred as "SITE"), please read the conditions below. If you do not accept these terms, please cease to use the "SITE." "SITE" owner reserves the right to change the information on the website, forms, contents, the "SITE," "SITE" terms of use anytime they want.

1.2. The owner of the "SITE" is Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. (From now on it is going to be referred as "Turkiye Klinikleri", shortly) and it resides at Turkocagi cad. No:30, 06520 Balgat Ankara. The services in the "SITE" are provided by "Turkiye Klinikleri."

1.3. Anyone accessing the "SITE" with or without a fee whether they are a natural person or a legal identity is considered to agree these terms of use. In this contract hereby, "Turkiye Klinikleri" may change the stated terms anytime. These changes will be published in the "SITE" periodically and they will be valid when they are published. Any natural person or legal identity benefiting from and reaching to the "SITE" are considered to be agreed to any change on hereby contract terms done by "Turkiye Klinikleri."

1.4. The "Terms of Use" hereby is published in the website with the last change on March 30th 2014 and the "SITE" is activated by enabling the access to everyone. The "Terms of Use" hereby is also a part of the any "USER Contract" was and/or will be done with the users using "Turkiye Klinikleri" services with or without a fee an inseparable.

2. DEFINITIONS

2.1. "SITE": A website offering different kind of services and context with a certain frame determined by "Turkiye Klinikleri" and it is accessible on-line on http://www.turkiyeklinikleri.com domain name and/or subdomains connected to the domain name.

2.2. USER: A natural person or a legal identity accessing to the "SITE" through online settings.

2.3. LINK: A link enabling to access to another website through the "SITE", the files, the context or through another website to the "SITE", the files and the context.

2.4. CONTEXT: Any visual, literary and auditory images published in the "Turkiye Klinikleri", "SITE" and/or any website or any accessible information, file, picture, number/figures, price, etc.

2.5. "USER CONTRACT": An electronically signed contract between a natural or a legal identity benefiting from special services "Turkiye Klinikleri" will provide and "Turkiye Klinikleri".

3. SCOPE OF THE SERVICES

3.1. "Turkiye Klinikleri" is completely free to determine the scope and quality of the services via the "SITE".

3.2. To benefit the services of "Turkiye Klinikleri" "SITE", the "USER" must deliver the features that will be specified by "Turkiye Klinikleri". "Turkiye Klinikleri" may change this necessity any time single-sided.

3.3. Not for a limited number, the services "Turkiye Klinikleri" will provide through the "SITE" for a certain price or for free are;

- Providing scientific articles, books and informative publications for health industry.

- Providing structural, statistical and editorial support to article preparation stage for scientific journals.

4. GENERAL PROVISIONS

4.1. "Turkiye Klinikleri" is completely free to determine which of the services and contents provided in the "SITE" will be charged.

4.2. People benefiting from the services provided by "Turkiye Klinikleri" and using the website can use the "SITE" only according to the law and only for personal reasons. Users have the criminal and civil liability for every process and action they take in the "SITE". Every USER agrees, declares and undertakes that they will not proceed by any function or action infringement of rights of "Turkiye Klinikleri"s and/or other third parties', they are the exclusive right holder on usage, processing, storage, made public and revealing any written, visual or auditory information reported to Turkiye Klinikleri" and/or "SITE" to the third parties. "USER" agrees and undertakes that s/he will not duplicate, copy, distribute, process, the pictures, text, visual and auditory images, video clips, files, databases, catalogs and lists within the "SITE", s/he will not be using these actions or with other ways to compete with "Turkiye Klinikleri", directly or indirectly.

4.3. The services provided and the context published within the "SITE" by third parties is not under the responsibility of "Turkiye Klinikleri", institutions collaborated with "Turkiye Klinikleri", "Turkiye Klinikleri" employee and directors, "Turkiye Klinikleri" authorized salespeople. Commitment to accuracy and legality of the published information, context, visual and auditory images provided by any third party are under the full responsibility of the third party. "Turkiye Klinikleri" does not promise and guarantee the safety, accuracy and legality of the services and context provided by a third party.

4.4. "USER"s cannot act against "Turkiye Klinikleri", other "USER"s and third parties by using the "SITE". "Turkiye Klinikleri" has no direct and/or indirect responsibility for any damage a third party suffered or will suffer regarding "USER"s actions on the "SITE" against the rules of the hereby "Terms of Use" and the law.

4.5. "USER"s accept and undertake that the information and context they provided to the "SITE" are accurate and legal. "Turkiye Klinikleri" is not liable and responsible for promising and guaranteeing the verification of the information and context transmitted to "Turkiye Klinikleri" by the "USER"s, or uploaded, changed and provided through the "SITE" by them and whether these information are safe, accurate and legal.

4.6. "USER"s agree and undertake that they will not perform any action leading to unfair competition, weakening the personal and commercial credit of "Turkiye Klinikleri" and a third party,  encroaching and attacking on personal rights within the "SITE" in accordance with the Turkish Commercial Code Law.

4.7. "Turkiye Klinikleri" reserves the right to change the services and the context within the "SITE"  anytime. "Turkiye Klinikleri" may use this right without any notification and timelessly. "USER"s have to make the changes and/or corrections "Turkiye Klinikleri" required immediately. Any changes and/or corrections that are required by "Turkiye Klinikleri", may be made by "Turkiye Klinikleri" when needed. Any harm, criminal and civil liability resulted or will result from changes and/or corrections required by "Turkiye Klinikleri" and were not made on time by the "USER"s belongs completely to the users.

4.8. "Turkiye Klinikleri" may give links through the "SITE" to other websites and/or "CONTEXT"s and/or folders that are outside of their control and owned and run by third parties. These links are provided for ease of reference only and do not hold qualification for support the respective web SITE or the admin or declaration or guarantee for the information inside. "Turkiye Klinikleri" does not hold any responsibility over the web-sites connected through the links on the "SITE", folders and context, the services or products on the websites provided through these links or their context.

4.9. "Turkiye Klinikleri" may use the information provided to them by the "USERS" through the "SITE" in line with the terms of the "PRIVACY POLICY" and "USER CONTRACT". It may process the information or classify and save them on a database. "Turkiye Klinikleri" may also use the USER's or visitor's identity, address, e-mail address, phone number, IP number, which sections of the "SITE" they visited, domain type, browser type, date and time information to provide statistical evaluation and customized services.

5. PROPRIETARY RIGHTS

5.1. The information accessed through this "SITE" or provided by the users legally and all the elements (including but not limited to design, text, image, html code and other codes) of the "SITE" (all of them will be called as studies tied to "Turkiye Klinikleri"s copyrights) belongs to "Turkiye Klinikleri". Users do not have the right to resell, process, share, distribute, display or give someone permission to access or to use the "Turkiye Klinikleri" services, "Turkiye Klinikleri" information and the products under copyright protection by "Turkiye Klinikleri". Within hereby "Terms of Use" unless explicitly permitted by "Turkiye Klinikleri" nobody can reproduce, process, distribute or produce or prepare any study from those under "Turkiye Klinikleri" copyright protection.

5.2. Within hereby "Terms of Use", "Turkiye Klinikleri" reserves the rights for "Turkiye Klinikleri" services, "Turkiye Klinikleri" information, the products associated with "Turkiye Klinikleri" copyrights, "Turkiye Klinikleri" trademarks, "Turkiye Klinikleri" trade looks or its all rights for other entity and information it has through this website unless it is explicitly authorized by "Turkiye Klinikleri".

6. CHANGES IN THE TERMS OF USE

"Turkiye Klinikleri" in its sole discretion may change the hereby "Terms of Use" anytime announcing within the "SITE". The changed terms of the hereby "Terms of Use" will become valid when they are announced. Hereby "Terms of Use" cannot be changed by unilateral declarations of users.

7. FORCE MAJEURE

"Turkiye Klinikleri" is not responsible for executing late or never of this hereby "Terms of Use", privacy policy and "USER Contract" in any situation legally taken into account as force majeure. Being late or failure of performance or non-defaulting of this and similar cases like this will not be the case from the viewpoint of "Turkiye Klinikleri", and "Turkiye Klinikleri" will not have any damage liability for these situations. "Force majeure" term will be regarded as outside of the concerned party's reasonable control and any situation that "Turkiye Klinikleri" cannot prevent even though it shows due diligence. Also, force majeure situations include but not limited to natural disasters, rebellion, war, strike, communication problems, infrastructure and internet failure, power cut and bad weather conditions.

8. LAW AND AUTHORISATION TO FOLLOW

Turkish Law will be applied in practicing, interpreting the hereby "Terms of Use" and managing the emerging legal relationships within this "Terms of Use" in case of finding element of foreignness, except for the rules of Turkish conflict of laws. Ankara Courts and Enforcement Offices are entitled in any controversy happened or may happen due to hereby contract.

9. CLOSING AND AGREEMENT

Hereby "Terms of Use" come into force when announced in the "SITE" by "Turkiye Klinikleri". The users are regarded to agree to hereby contract terms by using the "SITE". "Turkiye Klinikleri" may change the contract terms and the changes will be come into force by specifying the version number and the date of change on time it is published in the "SITE".

 

30.03.2014

Privacy Policy

We recommend you to read the terms of use below before you visit our website. In case you agree these terms, following our rules will be to your favor. Please read our Terms of Use thoroughly.

www.turkiyeklinikleri.com website belongs to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. and is designed in order to inform physicians in the field of health

www.turkiyeklinikleri.com cannot reach to user’s identity, address, service providers or other information. The users may send this information to the website through forms if they would like to. However, www.turkiyeklinikleri.com may collect your hardware and software information. The information consists of your IP address, browser type, operating system, domain name, access time, and related websites. www.turkiyeklinikleri.com cannot sell the provided user information (your name, e-mail address, home and work address, phone number) to the third parties, publish it publicly, or keep it in the website. Gathered information has a directing feature to be a source for the website’s visitor profile, reporting and promotion of the services.

www.turkiyeklinikleri.com uses the taken information:

-To enhance, improve and maintain the quality of the website

-To generate visitor’s profile and statistical data

-To determine the tendency of the visitors on using our website

-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

info@turkiyeklinikleri.com