Journal of Literature Pharmacy Sciences

Esansiyel Yağların Kozmetiklerde Güvenli KullanımıUlusal Yönlendirmeler: Geleneksel Derleme
Safety Usage of Essential Oils in Cosmetics-National Orientations: Traditional Review
Rana ÜLKER ÖZKANa,b, Sonia SANAJOUa, Pınar ERKEKOĞLUa, Terken BAYDARa
aHacettepe Üniversitesi Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Toksikoloji ABD, Ankara, Türkiye
bTürkiye İlaç ve Tıbbi Cihaz Kurumu, Kozmetik ve Biyosidal Ürünler Denetim Dairesi, Ankara, Türkiye
J Lit Pharm Sci. 2022;11(2):159-69
doi: 10.5336/pharmsci.2022-88271
Article Language: TR
Full Text
ÖZET
 Kişisel bakımda ilk olarak kozmetik ürünler akla gelmektedir ve kozmetikler, adeta bir gereklilik olarak günlük yaşantımıza girmiştir. Kozmetik ürün kullanımı, her toplum için vazgeçilmezdir. Esansiyel yağlar, yüzyıllardır kozmetik ürünlerde kullanılmakta olup; 'bitkiye özgü koku, tat veya her ikisini birden veren, bitkilerin uçucu ikincil metabolitleri' olarak tanımlanırlar. Esansiyel yağlar yapraklarda, gövdede, çiçek ve meyvelerde, ağaç kabuğunda ve bitkilerin köklerinde 'sıvı damlaları' olarak bulunurlar. Esansiyel yağların bileşimi; üretim şekline, yetiştirildiği bölgenin coğrafi yapısına ve iklime bağlı olarak değişmektedir. Esansiyel yağlar, eser miktarlarda bulunan diğer bileşenlere kıyasla oldukça yüksek konsantrasyonlarda (%20-70) 2-3 ana bileşen içerirler ve bu çok karmaşık karışımlarda temel olarak terpenler, terpenoidler ve fenilpropanoidler bulunur. Esansiyel yağların uzun yıllardır kullanılıyor olmaları, güven verici bir faktör gibi algılanabilir. Ancak bu yağlardan bazıları, kozmetik ürünlerde kullanıldığında dermal emilim veya inhalasyon yoluyla tüketiciler için tehlikeli olabilmektedir. Mevcut bilimsel yayınlar, genellikle sınırlı sayıdadır ve bu çalışmalar spesifik olarak esansiyel yağların kozmetik ürünlerde kullanımı ile bu yağların içerdiği bir veya daha fazla saf bileşeni tanımlamaktadır. Günümüzde kozmetik ürünlerde esansiyel yağların kullanımı popülerdir. Ancak bu yağların güvenlilikleri de sıkça tartışma konusudur. Dolayısıyla bu konudaki in vitro ve in vivo toksikoloji çalışmaları yetersiz kalmaktadır. Bu derlemede, esansiyel yağlarla ilgili ulusal ve uluslararası kılavuzlardan söz edilecek ve esansiyel yağların, kozmetik ürünlerde kullanımının genel güvenlilik değerlendirmeleri özetlenecektir.

Anahtar Kelimeler: Kozmetikler; kozmetik güvenliliği; esansiyel yağlar; kişisel bakım ürünleri; yasal düzenlemeler
ABSTRACT
 When it comes to personal care, cosmetic products come to mind and cosmetics have entered our daily lives as a necessity. The use of cosmetic products is indispensable for every society. Essential oils have been used in cosmetic products for centuries and are defined as 'volatile secondary metabolites of plants that impart a distinctive odor, taste, or both'. Essential oils are found as 'liquid drops' in leaves, stems, flowers and fruits, bark and roots of plants. The composition of essential oils varies depending on the production method, the geographical structure of the region where it is grown and the climate. Essential oils contain 2 to 3 main components in very high concentrations (20-70%) compared to other trace components, and these very complex mixtures mainly contain terpenes, terpenoids and phenylpropanoids. The fact that essential oils have been used for years can be perceived as a reassuring factor. However, some of these oils can be dangerous to consumers when used in cosmetic products by dermal absorption or inhalation. Current scientific publications are generally limited in number, and these studies specifically describe the use of essential oils in cosmetic products and one or more of the pure ingredients contained in these oils. Today, the use of essential oils in cosmetic products is popular. However, the safety of these oils is also the subject of frequent debate. Therefore, in vitro and in vivo toxicology studies on this subject are insufficient. This study reviews the national and international relevant guidelines and general safety assessments of cosmetic products. In this review, national and international guidelines on essential oils will be mentioned and general safety assessments of the use of essential oils in cosmetic products will be summarized.

Keywords: Cosmetics; cosmetic safety; essential oils; personal care products; legal regulations
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Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

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-During various attacks to the website,

-Disruption of the website because of a virus.

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Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

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