Turkiye Klinikleri Journal of Veterinary Sciences

.: ORIGINAL RESEARCH
İç Anadolu Bölgesi'nde Anti Enfeksiyöz Laringotrakeitis Virüsü Antikor Araştırması: Özgün Araştırma
Anti Infectious Laryngotracheitis Virus Antibody Investigation in the Central Anatolia Region: Original Research
Gülşen GONCAGÜLa, Özlem KARDOĞANb, Elçin GÜNAYDINc, Yavuz ÇOKALd
aBursa Uludağ Üniversitesi Mennan Pasinli Atçılık Meslek Yüksekokulu, Bursa, TÜRKİYE
bVeteriner Kontrol Merkez Araştırma Enstitüsü Müdürlüğü, Kanatlı Hayvan Hastalıkları Teşhis Laboratuvarı, Ankara, TÜRKİYE
cKastamonu Üniversitesi Veteriner Fakültesi, Mikrobiyoloji ABD, Kastamonu, TÜRKİYE d Bandırma Onyedi Eylül Üniversitesi Bandırma Meslek Yüksekokulu, Balıkesir, TÜRKİYE
Turkiye Klinikleri J Vet Sci. 2021;12(2):63-9
doi: 10.5336/vetsci.2021-84120
Article Language: TR
Full Text
ÖZET
 Amaç: Enfeksiyöz laringotrakeitis [infectious laryngotracheitis (ILT)], tüm dünyada kümes hayvanlarının ekonomik açıdan önemli bir viral solunum yolu hastalığıdır. Bu çalışmanın amacı, İç Anadolu Bölgesi'nde ticari yumurtacı sürü ve köy tavuklarında anti-ILT virüsü (ILTV) antikorları varlığını indirekt ELISA ile araştırmaktır. Gereç ve Yöntemler: İç Anadolu Bölgesi'nde 17 aşısız (n=268) ve 11 aşılı (n=465) olmak üzere 28 ticari yumurtacı sürüden (n=733) ve 7 farklı lokalizayonda bulunan köy tavuklarından (n=145) rastgele toplam 878 kan örneği alındı ve serumları çıkartıldı. Serum örneklerinde, ILTV'ye karşı oluşan antikorları tespit etmek için ticari indirekt ELISA kiti ile kullanıldı. Bulgular: İncelenen toplam 145 aşısız köy tavuğunda %86,90 (n=126), 268 aşısız ticari yumurtacıda %90,67 (n=243), 465 aşılı ticari yumurtacıda %35,70 (n=166) oranında anti-ILTV antikorlarına rastlandı. Aşılama yapılmasına rağmen 5 ticari yumurtacı sürüde ILTV'ye karşı antikor tespit edilmedi. Sonuç: İç Anadolu Bölgesi'nde özellikle aşısız ticari yumurtacı sürülerde ve köy tavuklarında ILT enfeksiyonunun ciddi risk yarattığı belirlendi. Kümeslerin birbirine yakınlığı dolayısıyla özellikle aşı kaynaklı saçılımın olabileceği öngörüsüyle, ILT salgınlarından izole edilen suşların filogenetik analizlerinin yapılıp, daha ileri çalışmalarda enfeksiyonun kaynağı üzerine eğilmenin daha doğru bir yaklaşım olacağı kanaatindeyiz.

Anahtar Kelimeler: Enfeksiyöz laringotrakeitis; ELISA; ticari yumurtacı tavuk; köy tavuğu
ABSTRACT
 Objective: Infectious laryngotracheitis (ILT) is an economically important viral respiratory disease of poultry around the world. The aim of this study is investigate the presence of anti-ILTV antibodies in commercial layers and village chickens in the Central Anatolia Region by indirek ELISA. Material and Methods: A total of 878 blood samples were collected from 28 commercial layer flocks (n=733) comprising 17 unvaccinated (n=268), 11 vaccinated (n=465), and village chickens (n=145) at 7 different localisation in the Central Anatolia Region. Sera were obtained from the collected blood samples. Anti-ILT virus (ILTV) antibodies were determined by commercial indirect ELISA kit. Results: Anti-ILTV antibodies were determined of the investigated 145 unvaccinated village chickens, 268 unvaccinated commercial layer chickens, and 465 vaccinated commercial layer chickens, at ratios of 86.90% (n=126), 90.67% (n=243), and 35.70% (n=166), respectively. Although 5 commercial layer flocks were vaccinated, no antibody response was detected. Conclusion: It was determined that ILT infection poses a serious risk especially in unvaccinated commercial layer flocks and village chickens in the Central Anatolia Region. We believe that it would be a more correct approach to conduct phylogenetic analyzes of strains isolated from ILT outbreaks and to focus on the source of infection in further studies, with the prediction of vaccine-induced spillage due to the proximity of the flocks.

Keywords: Infectious laryngotracheitis; ELISA; commercial layer chicken; village chicken
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