Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Karbodimidin Universal Adezivlerin Dentine Bağlanma Kuvveti Üzerine Etkisi: İn-Vitro Bir Çalışma
Effect of Carbodiimide on the Dentin Bond Strength of Universal Adhesives: An In-Vitro Study
Ayşe Nur DOĞANa, Soley ARSLANb
aNimet Bayraktar Ağız ve Diş Sağlığı Hastanesi, Restoratif Diş Tedavisi Kliniği, Kayseri, Türkiye
bErciyes Üniversitesi Diş Hekimliği Fakültesi, Restoratif Diş Tedavisi ABD, Kayseri, Türkiye
Turkiye Klinikleri J Dental Sci. 2023;29(1):166-75
doi: 10.5336/dentalsci.2022-91090
Article Language: TR
Full Text
ÖZET
 Amaç: Bu in vitro çalışmanın amacı, matriksmetalloproteinaz inhibitörü olan karbodimidin (1-etil-3-[3-dimetilaminopropil] carbodiimide) adeziv uygulaması öncesi dentin yüzey tedavisinde kullanıldığında universal adeziv sistemlerin dentine bağlanma dayanımı üzerine etkisinin mikrogerilim test yöntemiyle değerlendirilmesidir. Gereç ve Yöntemler: Bu araştırmada, 80 tane insan 3. molar dişten standart dentin yüzeyleri elde edilmiş ve rastgele 8 gruba ayrılmıştır. Grupların yarısına 1M karbodimid ile adeziv uygulaması öncesi yüzey tedavisi yapılırken, diğer yarısına uygulanmamıştır. Daha sonra bütün gruplara Single Bond Universal ve Clearfil Universal Bond hem etchand- rinse hem self-etch modunda kullanılarak uygulanmıştır. Örneklerin hepsi 4 mm kalınlığında 3M Filtek Bulk-Fill kompozit rezinle restore edilerek polimerize edilmiştir. Örnekler 24 saat distile suda bekletildikten sonra her grubun yarısı 6 ay yapay tükürükte saklanmıştır. Her örnekten 1 mm2lik yirmişer kesit alındıktan sonra mikrogerilim bağlanma dayanımı testi yapılmıştır. Mikrogerilim bağlanma dayanımı verilerini analiz etmek için hem 3 yönlü hem de tek yönlü varyans analizi ve 'post hoc' Tukey testi kullanılmıştır. Bulgular: Araştırma sonuçlarına göre test edilen erken dönem grupların mikrogerilim bağlanma dayanımı değerleri arasında istatistiksel olarak anlamlı farklılıklar bulunmazken (p>0,05), geç dönem grupların mikrogerilim bağlanma dayanımı değerleri arasında istatistiksel olarak anlamlı farklılıklar olduğu görülmüştür (p<0,05). Tüm grupların erken ve geç dönem bağlanma dayanımı değerleri arasında istatistiksel olarak anlamlı farklılıklar bulunmamıştır (p>0,05). Single Bond Universal'ın kullanıldığı grupların hepsi, Clearfil Universal Bond'un kullanıldığı gruplardan istatistiksel olarak anlamlı şekilde daha yüksek bağlanma dayanımı göstermişlerdir (p<0,05). Sonuç: Karbodimid kullanılan grupların erken ve geç dönem bağlanma değerleri arasında fark bulunmamıştır.

Anahtar Kelimeler: Dentine bağlanma dayanımı; biyoyıkım; karbodimid; matriksmetalloproteinaz; universal adezivler
ABSTRACT
 Objective: The aim of this in-vitro study is to evaluate the effect of universal adhesive systems on dentin bond strength by microtensile test method when carbodiimide (1-ethyl-3-[3-dimethylaminopropyl] carbodiimide), which is a matrix metalloproteinase inhibitor, is used in dentin surface treatment before adhesive application. Material and Methods: In this study, standard dentin surfaces were obtained from 80 human 3. molar teeth and randomly divided into 8 groups. Half of the groups were treated with 1M carbodimide before the adhesive application, while the other half did not. Then, Single Bond Universal and Clearfil Universal Bond were applied to all groups using either etch-and-rinse or self-etch modes. All samples were restored and polymerized with 4 mm thick 3M Filtek Bulk-Fill composite resin. After the samples were kept in distilled water for 24 hours, half of each group was stored in artificial saliva for 6 months. After taking 20 sections of 1 mm2 from each sample, microtensile bond strength test was performed. Three-way and one-way analysis of variance and post hoc Tukey test were used to analyze microtensile bond strength data. Results: According to the results of the study, while there was no statistically significant difference between the microtensile bond strength values of the tested early period groups (p>0.05), there were statistically significant differences between the microtensile bond strength values of the late period groups (p<0.05). There was no statistically significant difference between the early and late bond strength values of all groups (p>0.05). All of the groups in which Single Bond Universal was used showed significantly higher bond strength than the groups in which Clearfil Universal Bond was used (p<0.05). Conclusion: While there was no difference between the early and late bonding values of the groups in which carbodimide was used, an increase was observed in the bonding values of the groups in which Single Bond Universal was applied.

Keywords: Dentin bond strength; biodegradation; carbodimide; matrix metalloproteinase; universal adhesives
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