Turkiye Klinikleri Journal of Ophthalmology

.: ORIGINAL RESEARCH
Oküler Hipertansiyonlu Gözlerde Foveal Avasküler Zon
Foveal Avascular Zone in Eyes with Ocular Hypertension
Arif Ülkü YENERa
aKeçiören Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Kliniği, Ankara, TÜRKİYE
Turkiye Klinikleri J Ophthalmol. 2020;29(2):136-42
doi: 10.5336/ophthal.2019-71074
Article Language: TR
Full Text
ÖZET
 Amaç: Glokomda nöral ve korneal parametrelere ilave olarak bazı vasküler parametreler de etkilenir. Bu çalışmanın amacı, oküler hipertansiyonlu gözlerde vasküler yapıları ölçmek ve kıyaslamaktır. Gereç ve Yöntemler: Bir ya da 2 gözünde göz içi basıncı 21 mmHg'dan yüksek olan 19 hasta çalışmaya dâhil edildi. Hastalarda glokomatöz optik nöropati veya görme alanı kaybı bulunmuyordu. Hastaların 2 gözü ve kontrol kişilerin rastgele seçilen 1 gözünde yüzeysel ve derin foveal avasküler zon alanları, foveal ve parafoveal damar yoğunlukları ve koroid kalınlığı swept-source optikal koherens tomografi kullanılarak ölçüldü. Bulgular: Vasküler parametreler arasında, hastaların göz içi basıncı daha yüksek olan baskın gözlerinin derin foveal avasküler zon alanları kontrol grubu ile kıyaslandığında nispeten daha küçük olsa da bu farklılık istatistiksel olarak anlamlı değildi. Derin foveal avasküler zon alanı hastaların baskın olan gözlerinde 302,32±113,95 μm2, baskın olmayan diğer gözlerinde 317,16±109,89 μm2 olarak ölçülürken, bu parametre kontrol grubunu oluşturan kişilerde 414,33±215,72 μm2 idi. Bu parametre açısından baskın gözlerle kontrol gözleri ve baskın olmayan diğer gözlerle kontrol gözleri arasındaki istatistiksel fark sırasıyla p=0,065 ve p=0,10 düzeyinde idi. Yüzeysel foveal avasküler zon alanı, maküler damar yoğunluğu ve koroid kalınlığı gibi diğer vasküler parametreler de gruplar arasında farklı değildi. Sonuç: Bu çalışma, oküler hipertansiyonun makulada yüzeysel ve derin foveal avasküler zon alanlarını etkilemediğini göstermiştir.

Anahtar Kelimeler: Oküler hipertansiyon; foveal avasküler zon; damar yoğunluğu; koroid kalınlığı
ABSTRACT
 Objective: Certain vascular parameters are affected in glaucoma in addition to neural and corneal parameters. The aim of this study was to measure and compare vascular parameters in eyes with ocular hypertension. Material and Methods: Nineteen patients with intraocular pressure higher than 21 mmHg in one or both eyes were included in the study. Patients did not have glaucomatous optic neuropathy or visual field defect. Superficial and deep foveal avascular zone areas, foveal and parafoveal vessel densities and choroidal thickness in both eyes of patients and in a randomly selected eye of controls were measured by the swept-source optical coherence tomography. Results: Among the vascular parameters, although deep foveal avascular zone area of dominant eye with higher intraocular pressure of patients was relatively smaller compared to control group, this difference was not statistically significant. The deep foveal avascular zone area was 302.32±113.95 μm2 in dominant eyes of patients and 317.16±109.89 μm2 in non-dominant fellow eyes, while this parameter was 414.33±215.72 μm2 in the control group. The statistical difference between dominant eyes and control eyes and non-dominant fellow eyes and control eyes in terms of this parameter was p=0.065 and p=0.10, respectively. Other vascular parameters such as superficial foveal avascular zone area, macular vessel density and choroidal thickness did not differ between the groups. Conclusion: This study showed that ocular hypertension did not affect superficial and deep foveal avascular zone areas in macula.

Keywords: Ocular hypertension; foveal avascular zone; vessel density; choroidal thickness
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