Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Physicochemical Properties of Hydraulic Calcium Silicate Sealers in Comparison with Resin and Calcium Hydroxide-Based Sealers: An In Vitro Study
Hidrolik Kalsiyum Silikat Bazlı Kanal Patlarının Fizikokimyasal Özelliklerinin Rezin ve Kalsiyum Hidroksit Bazlı Kanal Patları ile Karşılaştırılması: İn Vitro Çalışma
Bahar TEKERa , Cangül KESKİNb , Hikmet AYDEMİRb
aClinic of Endodontics, Giresun Oral and Dental Health Center, Giresun, Türkiye
bDepartment of Endodontics, Ondokuz Mayıs University Faculty of Dentistry, Samsun, Türkiye
Turkiye Klinikleri J Dental Sci. 2024;30(1):83-91
doi: 10.5336/dentalsci.2023-98001
Article Language: EN
Full Text
ABSTRACT
 Objective: This study aimed to compare the physicochemical properties of 3 bioceramic sealers (NeoSealer Flo, WellRoot ST, and CeraSeal) with mineral trioxide aggregate-like sealer (MTA Fillapex ), epoxy resin-based sealer (AH Plus Jet), methacrylate resin-based sealer (EndoREZ), and calcium hydroxide/salicylate resin-based sealer (Apexit Plus) in terms of flow, setting time, film thickness, solubility, water absorption, radiopacity, immediate and delayed pH, compressive strength, and dimensional stability. Material and Methods: Flow, setting time, film thickness, and solubility of all sealers were evaluated by International Standards Organization (ISO) 6876:2012, while water absorption and radiopacity values were determined using ISO:4049:2019 and ISO:13116:2014, respectively. Five samples were prepared from sealers for each test (n=5). Data were analyzed with Kruskal-Wallis H test with 5% significance threshold. Results: Flow, setting time, film thickness, and radiopacity values of all canal sealers complied with ISO standards. The solubility of AH Plus Jet, EndoREZ sealers was acceptable, while those of NeoSealer Flo, Well-Root ST, CeraSeal, MTA Fillapex, and Apexit Plus showed greater solubility than recommended. The lowest pH value in freshly mixed samples was observed in EndoREZ sealer. Conclusion: All the sealers complied with ISO 6876:2012 and ISO 13116:2014 standards regarding flow, setting time, film thickness, and radiopacity. MTA Fillapex did not set during its reported working time. The solubility values of AH Plus Jet, EndoREZ pastes were found to comply with ISO 6876:2012 standards, while Apexit Plus and bioceramic sealers exceeded the threshold.

Keywords: Endodontics; epoxy resin-based root canal sealer; root canal filling materials
ÖZET
 Amaç: Bu çalışma, 3 farklı hidrolik kalsiyum silikat kanal patının (NeoSealer Flo, Well-Root ST ve CeraSeal) fizikokimyasal özelliklerini bir mineral trioksit agregat içeren kanal patı (MTA Fillapex), bir epoksi rezin bazlı kanal patı (AH Plus Jet), bir metakrilat rezin bazlı kanal patı (EndoREZ) ve bir kalsiyum hidroksit/salisilat reçine bazlı kanal patı (Apexit Plus) ile sertleşme zamanı, film kalınlığı, çözünürlük, su emilimi, radyoopasite, sertleşme esnasında ve sonrasındaki pH değerleri, baskı dayanımı ve boyutsal stabilite açısından karşılaştırmayı amaçlamıştır. Gereç ve Yöntemler: Akıcılık, sertleşme süresi, film kalınlığı, çözünürlük Uluslararası Standartlar Teşkilatı [International Standards Organization (ISO)] 6876:2012 ile değerlendirilirken su emme, radyoopasite, erken ve geç pH, basınç dayanımı ve boyutsal stabilite sırasıyla ISO:4049:2019 ve ISO:13116:2014 ile değerlendirildi. Her bir test için beşer örnek hazırlandı (n=5). Veriler %5 anlamlılık eşiği ile Kruskal-Wallis H testi ile istatistiksel olarak analiz edildi. Bulgular: Tüm kanal patlarının akıcılık, sertleşme süresi, film kalınlığı ve radyopaklık değerleri ISO standartlarına uygundu. AH Plus Jet, EndoREZ kanal patlarının çözünürlüğü kabul edilebilir düzeydeyken, NeoSealer Flo, Well-Root ST, CeraSeal, MTA Fillapex ve Apexit Plus arzu edilenden daha yüksek çözünürlük göstermiştir. Yeni karıştırılmış örneklerde en düşük pH değeri EndoREZ için bulundu. Sonuç: Bütün kanal patları akıcılık, sertleşme süresi, film kalınlığı ve radyoopasite açısından ISO 6876:2012 ve ISO 13116:2014 standartlarına uygun bulunmuştur. MTA Fillapex belirtilen sertleşme süresinde sertleşme göstermemiştir. AH Plus Jet ve EndoREZ patlarının çözünürlük değerleri ISO 6876:2012 standardına uygun bulunurken, Apexit Plus ve biyoseramik patlar standartta belirtilen eşiği aşmıştır.

Anahtar Kelimeler: Endodonti; epoksi-rezin bazlı kök kanal patları; kök kanal dolgu materyalleri
REFERENCES:
  1. Haapasalo M, Endal U, Zandi H, et al. Eradication of endodontic infection by instrumentation and irrigation solutions. Endod Topics. 2005;10(1):77-102. [Crossref] 
  2. Sundqvist G, Figdor D, Persson S, Sjögren U. Microbiologic analysis of teeth with failed endodontic treatment and the outcome of conservative re-treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;85(1):86-93. [Crossref]  [PubMed] 
  3. Branstetter J, von Fraunhofer JA. The physical properties and sealing action of endodontic sealer cements: a review of the literature. J Endod. 1982;8(7):312-6. [Crossref]  [PubMed] 
  4. Silva EJNL, Cardoso ML, Rodrigues JP, De-Deus G, Fidalgo TKDS. Solubility of bioceramic- and epoxy resin-based root canal sealers: A systematic review and meta-analysis. Aust Endod J. 2021;47(3):690-702. [Crossref]  [PubMed] 
  5. Duarte MA, Ordinola-Zapata R, Bernardes RA, Bramante CM, Bernardineli N, Garcia RB, et al. Influence of calcium hydroxide association on the physical properties of AH Plus. J Endod. 2010;36(6):1048-51. [Crossref]  [PubMed] 
  6. Prati C, Gandolfi MG. Calcium silicate bioactive cements: Biological perspectives and clinical applications. Dent Mater. 2015;31(4):351-70. [Crossref]  [PubMed] 
  7. Huang G, Liu SY, Wu JL, Qiu D, Dong YM. A novel bioactive glass-based root canal sealer in endodontics. J Dent Sci. 2022;17(1):217-24. [Crossref]  [PubMed]  [PMC] 
  8. Williams DF. Definitions in Biomaterials: Proceedings of a Consensus Conference of the European Society for Biomaterials. 1st ed. Amsterdam: Elsevier; 1987.
  9. Kharouf N, Arntz Y, Eid A, Zghal J, Sauro S, Haikel Y, et al. Physicochemical and antibacterial properties of novel, premixed calcium silicate-based sealer compared to powder-liquid bioceramic sealer. J Clin Med. 2020;9(10):3096. [Crossref]  [PubMed]  [PMC] 
  10. Khalil I, Naaman A, Camilleri J. Properties of tricalcium silicate sealers. J Endod. 2016;42(10):1529-35. [Crossref]  [PubMed] 
  11. Park MG, Kim IR, Kim HJ, Kwak SW, Kim HC. Physicochemical properties and cytocompatibility of newly developed calcium silicate-based sealers. Aust Endod J. 2021;47(3):512-9. [Crossref]  [PubMed] 
  12. López-García S, Myong-Hyun B, Lozano A, García-Bernal D, Forner L, Llena C, et al. Cytocompatibility, bioactivity potential, and ion release of three premixed calcium silicate-based sealers. Clin Oral Investig. 2020;24(5):1749-59. [Crossref]  [PubMed] 
  13. Jo SB, Kim HK, Lee HN, Kim YJ, Dev Patel K, Campbell Knowles J, et al. Physical Properties and Biofunctionalities of Bioactive Root Canal Sealers In Vitro. Nanomaterials (Basel). 2020;10(9):1750. [Crossref]  [PubMed]  [PMC] 
  14. Avalonbiomed [Internet]. ©2023 Avalon Biomed [May 16, 2023]. NeoSealer Flo. Available from: [Link] 
  15. International Organization for Standardization. Dentistry-Root Canal Sealing Materials. ISO 6876. London, UK: British Standards Institution; 2012.
  16. Marín-Bauza GA, Silva-Sousa YT, da Cunha SA, Rached-Junior FJ, Bonetti-Filho I, Sousa-Neto MD, et al. Physicochemical properties of endodontic sealers of different bases. J Appl Oral Sci. 2012;20(4):455-61. [Crossref]  [PubMed]  [PMC] 
  17. Candeiro GT, Correia FC, Duarte MA, Ribeiro-Siqueira DC, Gavini G. Evaluation of radiopacity, pH, release of calcium ions, and flow of a bioceramic root canal sealer. J Endod. 2012;38(6):842-5. [Crossref]  [PubMed] 
  18. Yamauchi S, Watanabe S, Okiji T. Effects of heating on the physical properties of premixed calcium silicate-based root canal sealers. J Oral Sci. 2020;63(1):65-9. [Crossref]  [PubMed] 
  19. Zordan-Bronzel CL, Esteves Torres FF, Tanomaru-Filho M, Chávez-Andrade GM, Bosso-Martelo R, Guerreiro-Tanomaru JM. Evaluation of physicochemical properties of a new calcium silicate-based sealer, bio-c sealer. J Endod. 2019;45(10):1248-52. [Crossref]  [PubMed] 
  20. Mendes AT, Silva PBD, Só BB, Hashizume LN, Vivan RR, Rosa RAD, et al. Evaluation of physicochemical properties of new calcium silicate-based sealer. Braz Dent J. 2018;29(6):536-40. [Crossref]  [PubMed] 
  21. Vitti RP, Prati C, Silva EJ, Sinhoreti MA, Zanchi CH, de Souza e Silva MG, et al. Physical properties of MTA Fillapex sealer. J Endod. 2013;39(7):915-8. [Crossref]  [PubMed] 
  22. Prüllage RK, Urban K, Schäfer E, Dammaschke T. Material properties of a tricalcium silicate-containing, a mineral trioxide aggregate-containing, and an epoxy resin-based root canal sealer. J Endod. 2016;42(12):1784-8. [Crossref]  [PubMed] 
  23. de Almeida WC, de Carvalho Barros BM, de Meneses Aragão Ramos I, Ferraz MÂAL, Falcão CAM. Evaluation of physico-chemical properties, time of hardening and draining of an endodontic sealer added to mta in different proportions. Rev. Bras. Odontol. 2019;76(1):1. [Crossref] 
  24. Zhou HM, Shen Y, Zheng W, Li L, Zheng YF, Haapasalo M. Physical properties of 5 root canal sealers. J Endod. 2013;39(10):1281-6. [Crossref]  [PubMed] 
  25. Lee JK, Kwak SW, Ha JH, Lee W, Kim HC. Physicochemical properties of epoxy resin-based and bioceramic-based root canal sealers. Bioinorg Chem Appl. 2017;2017:2582849. [Crossref]  [PubMed]  [PMC] 
  26. Weisman MI. A study of the flow rate of ten root canal sealers. Oral Surg Oral Med Oral Pathol. 1970;29(2):255-61. [Crossref]  [PubMed] 
  27. Moinzadeh AT, Aznar Portoles C, Schembri Wismayer P, Camilleri J. Bioactivity Potential of EndoSequence BC RRM Putty. J Endod. 2016;42(4):615-21. [Crossref]  [PubMed] 
  28. Silva EJNL, Ferreira CM, Pinto KP, Barbosa AFA, Colaço MV, Sassone LM. Influence of variations in the environmental pH on the solubility and water sorption of a calcium silicate-based root canal sealer. Int Endod J. 2021;54(8):1394-402. [Crossref]  [PubMed] 
  29. Tanomaru-Filho M, Torres FFE, Chávez-Andrade GM, de Almeida M, Navarro LG, Steier L, et al. Physicochemical properties and volumetric change of silicone/bioactive glass and calcium silicate-based endodontic sealers. J Endod. 2017;43(12):2097-101. [Crossref]  [PubMed] 
  30. Kebudi Benezra M, Schembri Wismayer P, Camilleri J. Influence of environment on testing of hydraulic sealers. Sci Rep. 2017;7(1):17927. Erratum in: Sci Rep. 2018;8(1):7209. [Crossref]  [PubMed]  [PMC] 
  31. Gandolfi MG, Siboni F, Primus CM, Prati C. Ion release, porosity, solubility, and bioactivity of MTA Plus tricalcium silicate. J Endod. 2014;40(10):1632-7. [Crossref]  [PubMed] 
  32. Lim M, Jung C, Shin DH, Cho YB, Song M. Calcium silicate-based root canal sealers: a literature review. Restor Dent Endod. 2020;45(3):e35. [Crossref]  [PubMed]  [PMC] 
  33. Almeida MM, Rodrigues CT, Matos AA, Carvalho KK, Silva EJ, Duarte MA, et al. Analysis of the physicochemical properties, cytotoxicity and volumetric changes of AH Plus, MTA Fillapex and TotalFill BC Sealer. J Clin Exp Dent. 2020;12(11):e1058-e65. [Crossref]  [PubMed]  [PMC] 
  34. Okabe T, Sakamoto M, Takeuchi H, Matsushima K. Effects of pH on mineralization ability of human dental pulp cells. J Endod. 2006;32(3):198-201. [Crossref]  [PubMed] 
  35. Yang Q, Troczynski T, Liu DM. Influence of apatite seeds on the synthesis of calcium phosphate cement. Biomaterials. 2002;23(13):2751-60. [Crossref]  [PubMed] 

.: Up To Date

Login

 Forgot your password?

 New Registration  

Contact

Ortadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş.

.: Address

Turkocagi Caddesi No:30 06520 Balgat / ANKARA
Phone: +90 312 286 56 56
Fax: +90 312 220 04 70
E-mail: info@turkiyeklinikleri.com

.: Manuscript Editing Department

Phone: +90 312 286 56 56/ 2
E-mail: yaziisleri@turkiyeklinikleri.com

.: English Language Redaction

Phone: +90 312 286 56 56/ 145
E-mail: tkyayindestek@turkiyeklinikleri.com

.: Marketing Sales-Project Department

Phone: +90 312 286 56 56/ 142
E-mail: reklam@turkiyeklinikleri.com

.: Subscription and Public Relations Department

Phone: +90 312 286 56 56/ 118
E-mail: abone@turkiyeklinikleri.com

.: Customer Services

Phone: +90 312 286 56 56/ 118
E-mail: satisdestek@turkiyeklinikleri.com

1. TERMS OF USE

1.1. To use the web pages with http://www.turkiyeklinikleri.com domain name or the websites reached through the sub domain names attached to the domain name (They will be collectively referred as "SITE"), please read the conditions below. If you do not accept these terms, please cease to use the "SITE." "SITE" owner reserves the right to change the information on the website, forms, contents, the "SITE," "SITE" terms of use anytime they want.

1.2. The owner of the "SITE" is Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. (From now on it is going to be referred as "Turkiye Klinikleri", shortly) and it resides at Turkocagi cad. No:30, 06520 Balgat Ankara. The services in the "SITE" are provided by "Turkiye Klinikleri."

1.3. Anyone accessing the "SITE" with or without a fee whether they are a natural person or a legal identity is considered to agree these terms of use. In this contract hereby, "Turkiye Klinikleri" may change the stated terms anytime. These changes will be published in the "SITE" periodically and they will be valid when they are published. Any natural person or legal identity benefiting from and reaching to the "SITE" are considered to be agreed to any change on hereby contract terms done by "Turkiye Klinikleri."

1.4. The "Terms of Use" hereby is published in the website with the last change on March 30th 2014 and the "SITE" is activated by enabling the access to everyone. The "Terms of Use" hereby is also a part of the any "USER Contract" was and/or will be done with the users using "Turkiye Klinikleri" services with or without a fee an inseparable.

2. DEFINITIONS

2.1. "SITE": A website offering different kind of services and context with a certain frame determined by "Turkiye Klinikleri" and it is accessible on-line on http://www.turkiyeklinikleri.com domain name and/or subdomains connected to the domain name.

2.2. USER: A natural person or a legal identity accessing to the "SITE" through online settings.

2.3. LINK: A link enabling to access to another website through the "SITE", the files, the context or through another website to the "SITE", the files and the context.

2.4. CONTEXT: Any visual, literary and auditory images published in the "Turkiye Klinikleri", "SITE" and/or any website or any accessible information, file, picture, number/figures, price, etc.

2.5. "USER CONTRACT": An electronically signed contract between a natural or a legal identity benefiting from special services "Turkiye Klinikleri" will provide and "Turkiye Klinikleri".

3. SCOPE OF THE SERVICES

3.1. "Turkiye Klinikleri" is completely free to determine the scope and quality of the services via the "SITE".

3.2. To benefit the services of "Turkiye Klinikleri" "SITE", the "USER" must deliver the features that will be specified by "Turkiye Klinikleri". "Turkiye Klinikleri" may change this necessity any time single-sided.

3.3. Not for a limited number, the services "Turkiye Klinikleri" will provide through the "SITE" for a certain price or for free are;

- Providing scientific articles, books and informative publications for health industry.

- Providing structural, statistical and editorial support to article preparation stage for scientific journals.

4. GENERAL PROVISIONS

4.1. "Turkiye Klinikleri" is completely free to determine which of the services and contents provided in the "SITE" will be charged.

4.2. People benefiting from the services provided by "Turkiye Klinikleri" and using the website can use the "SITE" only according to the law and only for personal reasons. Users have the criminal and civil liability for every process and action they take in the "SITE". Every USER agrees, declares and undertakes that they will not proceed by any function or action infringement of rights of "Turkiye Klinikleri"s and/or other third parties', they are the exclusive right holder on usage, processing, storage, made public and revealing any written, visual or auditory information reported to Turkiye Klinikleri" and/or "SITE" to the third parties. "USER" agrees and undertakes that s/he will not duplicate, copy, distribute, process, the pictures, text, visual and auditory images, video clips, files, databases, catalogs and lists within the "SITE", s/he will not be using these actions or with other ways to compete with "Turkiye Klinikleri", directly or indirectly.

4.3. The services provided and the context published within the "SITE" by third parties is not under the responsibility of "Turkiye Klinikleri", institutions collaborated with "Turkiye Klinikleri", "Turkiye Klinikleri" employee and directors, "Turkiye Klinikleri" authorized salespeople. Commitment to accuracy and legality of the published information, context, visual and auditory images provided by any third party are under the full responsibility of the third party. "Turkiye Klinikleri" does not promise and guarantee the safety, accuracy and legality of the services and context provided by a third party.

4.4. "USER"s cannot act against "Turkiye Klinikleri", other "USER"s and third parties by using the "SITE". "Turkiye Klinikleri" has no direct and/or indirect responsibility for any damage a third party suffered or will suffer regarding "USER"s actions on the "SITE" against the rules of the hereby "Terms of Use" and the law.

4.5. "USER"s accept and undertake that the information and context they provided to the "SITE" are accurate and legal. "Turkiye Klinikleri" is not liable and responsible for promising and guaranteeing the verification of the information and context transmitted to "Turkiye Klinikleri" by the "USER"s, or uploaded, changed and provided through the "SITE" by them and whether these information are safe, accurate and legal.

4.6. "USER"s agree and undertake that they will not perform any action leading to unfair competition, weakening the personal and commercial credit of "Turkiye Klinikleri" and a third party,  encroaching and attacking on personal rights within the "SITE" in accordance with the Turkish Commercial Code Law.

4.7. "Turkiye Klinikleri" reserves the right to change the services and the context within the "SITE"  anytime. "Turkiye Klinikleri" may use this right without any notification and timelessly. "USER"s have to make the changes and/or corrections "Turkiye Klinikleri" required immediately. Any changes and/or corrections that are required by "Turkiye Klinikleri", may be made by "Turkiye Klinikleri" when needed. Any harm, criminal and civil liability resulted or will result from changes and/or corrections required by "Turkiye Klinikleri" and were not made on time by the "USER"s belongs completely to the users.

4.8. "Turkiye Klinikleri" may give links through the "SITE" to other websites and/or "CONTEXT"s and/or folders that are outside of their control and owned and run by third parties. These links are provided for ease of reference only and do not hold qualification for support the respective web SITE or the admin or declaration or guarantee for the information inside. "Turkiye Klinikleri" does not hold any responsibility over the web-sites connected through the links on the "SITE", folders and context, the services or products on the websites provided through these links or their context.

4.9. "Turkiye Klinikleri" may use the information provided to them by the "USERS" through the "SITE" in line with the terms of the "PRIVACY POLICY" and "USER CONTRACT". It may process the information or classify and save them on a database. "Turkiye Klinikleri" may also use the USER's or visitor's identity, address, e-mail address, phone number, IP number, which sections of the "SITE" they visited, domain type, browser type, date and time information to provide statistical evaluation and customized services.

5. PROPRIETARY RIGHTS

5.1. The information accessed through this "SITE" or provided by the users legally and all the elements (including but not limited to design, text, image, html code and other codes) of the "SITE" (all of them will be called as studies tied to "Turkiye Klinikleri"s copyrights) belongs to "Turkiye Klinikleri". Users do not have the right to resell, process, share, distribute, display or give someone permission to access or to use the "Turkiye Klinikleri" services, "Turkiye Klinikleri" information and the products under copyright protection by "Turkiye Klinikleri". Within hereby "Terms of Use" unless explicitly permitted by "Turkiye Klinikleri" nobody can reproduce, process, distribute or produce or prepare any study from those under "Turkiye Klinikleri" copyright protection.

5.2. Within hereby "Terms of Use", "Turkiye Klinikleri" reserves the rights for "Turkiye Klinikleri" services, "Turkiye Klinikleri" information, the products associated with "Turkiye Klinikleri" copyrights, "Turkiye Klinikleri" trademarks, "Turkiye Klinikleri" trade looks or its all rights for other entity and information it has through this website unless it is explicitly authorized by "Turkiye Klinikleri".

6. CHANGES IN THE TERMS OF USE

"Turkiye Klinikleri" in its sole discretion may change the hereby "Terms of Use" anytime announcing within the "SITE". The changed terms of the hereby "Terms of Use" will become valid when they are announced. Hereby "Terms of Use" cannot be changed by unilateral declarations of users.

7. FORCE MAJEURE

"Turkiye Klinikleri" is not responsible for executing late or never of this hereby "Terms of Use", privacy policy and "USER Contract" in any situation legally taken into account as force majeure. Being late or failure of performance or non-defaulting of this and similar cases like this will not be the case from the viewpoint of "Turkiye Klinikleri", and "Turkiye Klinikleri" will not have any damage liability for these situations. "Force majeure" term will be regarded as outside of the concerned party's reasonable control and any situation that "Turkiye Klinikleri" cannot prevent even though it shows due diligence. Also, force majeure situations include but not limited to natural disasters, rebellion, war, strike, communication problems, infrastructure and internet failure, power cut and bad weather conditions.

8. LAW AND AUTHORISATION TO FOLLOW

Turkish Law will be applied in practicing, interpreting the hereby "Terms of Use" and managing the emerging legal relationships within this "Terms of Use" in case of finding element of foreignness, except for the rules of Turkish conflict of laws. Ankara Courts and Enforcement Offices are entitled in any controversy happened or may happen due to hereby contract.

9. CLOSING AND AGREEMENT

Hereby "Terms of Use" come into force when announced in the "SITE" by "Turkiye Klinikleri". The users are regarded to agree to hereby contract terms by using the "SITE". "Turkiye Klinikleri" may change the contract terms and the changes will be come into force by specifying the version number and the date of change on time it is published in the "SITE".

 

30.03.2014

Privacy Policy

We recommend you to read the terms of use below before you visit our website. In case you agree these terms, following our rules will be to your favor. Please read our Terms of Use thoroughly.

www.turkiyeklinikleri.com website belongs to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. and is designed in order to inform physicians in the field of health

www.turkiyeklinikleri.com cannot reach to user’s identity, address, service providers or other information. The users may send this information to the website through forms if they would like to. However, www.turkiyeklinikleri.com may collect your hardware and software information. The information consists of your IP address, browser type, operating system, domain name, access time, and related websites. www.turkiyeklinikleri.com cannot sell the provided user information (your name, e-mail address, home and work address, phone number) to the third parties, publish it publicly, or keep it in the website. Gathered information has a directing feature to be a source for the website’s visitor profile, reporting and promotion of the services.

www.turkiyeklinikleri.com uses the taken information:

-To enhance, improve and maintain the quality of the website

-To generate visitor’s profile and statistical data

-To determine the tendency of the visitors on using our website

-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

info@turkiyeklinikleri.com