Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Süt Dişlerinde Ferrik Sülfat Amputasyonun İki Yıllık Başarısının Retrospektif Değerlendirmesi
Retrospective Evaluation of Two-Year Success of Ferric Sulfate Pulpotomy in Primary Teeth
Pınar DEMİRa, Merve BİLMEZ SELENa
aİnönü Üniversitesi Diş Hekimliği Fakültesi, Çocuk Diş Hekimliği ABD, Malatya, TÜRKİYE
Turkiye Klinikleri J Dental Sci. 2021;27(3):399-405
doi: 10.5336/dentalsci.2020-77978
Article Language: TR
Full Text
ÖZET
 Amaç: Ferrik sülfat (FS), süt dişi amputasyonu için uygun, başarı oranı yüksek ve düşük maliyetli bir alternatif pulpa kaplama malzemesi olarak kabul edilmektedir. Bu çalışmadaki amaç, süt dişine uygulanan FS amputasyonunun 2 yıllık başarısını retrospektif olarak değerlendirmektir. Gereç ve Yöntemler: Bu çalışmada, 1 Ocak 2015 ile 31 Aralık 2017 tarihleri arasında İnönü Üniversitesi Diş Hekimliği Fakültesi Pedodonti Anabilim Dalı'nda süt azı dişlerine FS amputasyonu uygulanmış hastaların kayıtları tarandı. Konsültan olarak tek uzman hekim tarafından endikasyonu koyulan ve her aşaması kontrol edilen, stajyer öğrenciler ya da uzmanlık eğitimi alan lisansüstü öğrenciler tarafından yapılan amputasyonlar çalışmaya dâhil edildi. Hastaların FS amputasyonu öncesi alınan teşhis radyografisi ile an az 2 yıl sonraki kontrol radyografileri değerlendirilerek, amputasyon başarı oranı hesaplandı. Amputasyondan 2 yıl ve sonrasında çekilen kontrol filminde, internal ya da eksternal kök rezorpsiyonunun gözlenmesi, periodontal aralığında genişleme/kesinti ya da furkasyon defekti görülen dişler başarısız kabul edildi. Bulgular: Taranan 2.408 süt azı dişinden 502 tanesi dâhil edilme kriterlerine uygun bulundu. Beş yüz iki dişin 120'sine yapılan FS amputasyonu başarısızken, 382 dişte ise tedavi başarılı olmuştur. FS amputasyonunun başarı oranı %76 olarak değerlendirilmiştir ve literatürle uyumludur. Çalışmadaki radyografik olarak başarısız tedavilerin tamamı, internal veya eksternal rezorpsiyon sonrası çekim yapılan dişlerdir. Sonuç: Bu çalışmada, stajyer öğrenciler ve uzmanlık öğrencileri tarafından yapılan FS amputasyonunun başarı oranı %76 olarak değerlendirilmiştir.

Anahtar Kelimeler: Süt dişi; amputasyon; pulpotomi; ferrik sülfat
ABSTRACT
 Objective: Ferric sulfate (FS) has been considered as an alternative pulp capping material suitable for primary teeth pulpotomy with high success rate and low cost. The aim of this study is to evaluate the 2-year success of FS amputation applied to the primary tooth retrospectively. Material and Methods: The current study, the records of patients who underwent FS amputation on primary molar teeth at the pedodontics department of an Pediatric Dentistry Department of Inonu University Faculty of Dentistry, between 1.1.2015-31.12.2017, were scanned. Amputations made by trainee students or postgraduate students with specialist training, who were consulted by the same pediatric dentist, were included in the study. The amputation success rate was calculated by evaluating diagnostic radiography taken before FS amputation and control radiographs after at least 2 years later. In the control film taken 2 years after amputation, teeth with internal or external root resorption, periodontal enlargement/interruption or furcation defect were accepted to be unsuccessful. Results: Out of 2,408 primary molars scanned, 502 were found to be suitable for inclusion criteria. While FS amputation of 120 of 502 teeth failed, treatment of 382 teeth was successful. The success rate of FS amputation was evaluated as 76% and it is compatible with the literature. All of the radiographically unsuccessful treatments in the study were teeth extracted after internal or external resorption. Conclusion: In this study, the success rate of FS amputation performed by intern students and residents was evaluated as 76%.

Keywords: Deciduous tooth; amputation; pulpotomy; ferric sulfate
REFERENCES:
  1. Olczak-Kowalczyk D, Samul M, Góra J, Gozdowski D, Turska-Szybka A. Ferric sulfate and formocresol pulpotomies in paediatric dental practice. A prospective-retrospective study. Eur J Paediatr Dent. 2019;20(1):27-32. [PubMed] 
  2. Selvi Kuvvetli S, Sungurtekin Ekçi E. Süt dişlerinde pulpa tedavileri. Özdemir Özenen D, editör. Pedodonti Akıl Notları. 2. Baskı. Ankara: Güneş Tıp Kitabevi; 2020. p.223.
  3. Odabaş ME, Alaçam A, Sillelioğlu H, Deveci C. Clinical and radiographic success rates of mineral trioxide aggregate and ferric sulphate pulpotomies performed by dental students. Eur J Paediatr Dent. 2012;13(2):118-22. [PubMed] 
  4. Kaptan A, Çukurcu Ç. Süt dişi amputasyon tedavilerinde güncel yaklaşımlar [Current approaches to primary teeth amputation therapies]. Turkiye Klinikleri J Dental Sci. 2020;26(1):122-31. [Crossref] 
  5. Moretti AB, Sakai VT, Oliveira TM, Fornetti AP, Santos CF, Machado MA, et al. The effectiveness of mineral trioxide aggregate, calcium hydroxide and formocresol for pulpotomies in primary teeth. Int Endod J. 2008;41(7):547-55. [Crossref]  [PubMed] 
  6. Lopes CS, Junqueira MA, Cosme-Silva L, Pegoraro COR, Garbelini CCD, Oliveira TM, et al. Initial inflammatory response after the pulpotomy of rat molars with MTA or ferric sulfate. J Appl Oral Sci. 2019;27:e20180550. [Crossref] 
  7. Fuks AB. Vital pulp therapy with new materials for primary teeth: new directions and Treatment perspectives. Pediatr Dent. 2008;30(3):211-9. [PubMed] 
  8. Koch G, Poulsen S, eds. Aren G, çeviri editörü. Çocuk Diş Hekimliğine Klinik Yaklaşım. 2. Baskı. İstanbul: Rotatif Yayınevi; 2012. p.157-8.
  9. Fuks AB, Holan G, Davis JM, Eidelman E. Ferric sulfate versus dilute formocresol in pulpotomized primary molars: long-term follow up. Pediatr Dent. 1997;19(5):327-30. [PubMed] 
  10. Camp JH, Fuks AB. Pediatric endodontics: Endodontic treatment fort he primary and young permanent dentition. In: Cohen S, Hargreaves KM, eds. Pathways of the Pulp. 9th ed. London: Mosby Elseiver; 2006. p.822-53. [Link] 
  11. Aeinehchi M, Dadvand S, Fayazi S, Bayat-Movahed S. Randomized controlled trial of mineral trioxide aggregate and formocresol for pulpotomy in primary molar teeth. Int Endod J. 2007;40(4):261-7. [Crossref]  [PubMed] 
  12. Casas MJ, Kenny DJ, Johnston DH, Judd PL. Long-term outcomes of primary molar ferric sulfate pulpotomy and root canal therapy. Pediatr Dent. 2004;26(1):44-8. [PubMed] 
  13. Fernández CC, Martínez SS, Jimeno FG, Lorente Rodríguez AI, Mercadé M. Clinical and radiographic outcomes of the use of four dressing materials in pulpotomized primary molars: a randomized clinical trial with 2-year follow-up. Int J Paediatr Dent. 2013;23(6):400-7. [Crossref]  [PubMed] 
  14. Alaçam A. Pedodontide endodontik yaklaşımlar. Alaçam T, Uzel G, Alaçam A, Aydın M, editörler. Endodonti. 2. Baskı. Ankara: Barış Yayınları; 2000. p.693-722.
  15. Cleaton-Jones P, Duggal M, Parak M, William S, Setze S. Ferric sulphate and formocresol pulpotomies in baboon primary molars: histological responses. Eur J Paediatr Dent. 2002;3(3):121-5. [PubMed] 
  16. Fei AL, Udin RD, Johnson R. A clinical study of ferric sulfate as a pulpotomy agent in primary teeth. Pediatr Dent. 1991;13(6):327-32. [PubMed] 
  17. Smith NL, Seale NS, Nunn ME. Ferric sulfate pulpotomy in primary molars: a retrospective study. Pediatr Dent. 2000;22(3):192-9. [PubMed] 
  18. Ranly DM. Pulpotomy therapy in primary teeth: new modalities for old rationales. Pediatr Dent. 1994;16(6):403-9. [PubMed] 
  19. Lemon RR, Steele PJ, Jeansonne BG. Ferric sulfate hemostasis: effect on osseous wound healing. Left in situ for maximum exposure. J Endod. 1993;19(4):170-3. [Crossref]  [PubMed] 
  20. Peng L, Ye L, Guo X, Tan H, Zhou X, Wang C, et al. Evaluation of formocresol versus ferric sulphate primary molar pulpotomy: a systematic review and meta-analysis. Int Endod J. 2007;40(10):751-7. [Crossref]  [PubMed] 
  21. Yildiz E, Tosun G. Evaluation of formocresol, calcium hydroxide, ferric sulfate, and MTA primary molar pulpotomies. Eur J Dent. 2014;8(2):234-40. [Crossref]  [PubMed]  [PMC] 
  22. Salako N, Joseph B, Ritwik P, Salonen J, John P, Junaid TA. Comparison of bioactive glass, mineral trioxide aggregate, ferric sulfate, and formocresol as pulpotomy agents in rat molar. Dent Traumatol. 2003;19(6):314-20. [Crossref]  [PubMed] 
  23. Cotes O, Boj JR, Canalda C, Carreras M. Pulpal tissue reaction to formocresol vs. ferric sulfate in pulpotomized rat teeth. J Clin Pediatr Dent. 1997;21(3):247-53. [PubMed] 
  24. Ibricevic H, al-Jame Q. Ferric sulfate as pulpotomy agent in primary teeth: twenty month clinical follow-up. J Clin Pediatr Dent. 2000;24(4):269-72. [Crossref]  [PubMed] 
  25. Fuks AB. Pulp therapy for the primary dentition. In: Pinkham J, Casamassimo P, Fields H, McTigue D, Nowak A, eds. Pediatric Dentistry: Infancy Through Adolescence. 4th ed. St Louis, Missouri: Elsevier Saunders; 2005. p.375-93. [Link] 
  26. Ranly DM, Garcia-Godoy F. Reviewing pulp treatment for primary teeth. J Am Dent Assoc. 1991;122(9):83-5. [Crossref]  [PubMed] 
  27. Patchett CL, Srinivasan V, Waterhouse PJ. Is there life after Buckley's formocresol? Part II - Development of a protocol for the management of extensive caries in the primary molar. Int J Paediatr Dent. 2006;16(3):199-206. [Crossref]  [PubMed] 
  28. Kilpatrick N, Seow WK, Cameron AC, Widmer RP. Pulp therapy for primary and young permanent teeth. In: Cameron AC, Widmer RP, eds. Handbook of Pediatric Dentistry. 2nd ed. St Louis, Missouri: Mosby; 2003. p.71-85. [Link] 
  29. Coll JA, Seale NS, Vargas K, Marghalani AA, Al Shamali S, Graham L. Primary tooth vital pulp therapy: a systematic review and meta-analysis. Pediatr Dent. 2017;39(1):16-123. [PubMed] 
  30. International Agency for Research on Cancer, WHO. 2004; Press Release No. 153, June 15. [Link] 
  31. Mejàre I, Hasselgren G, Hammarström LE. Effect of formaldehyde-containing drugs on human dental pulp evaluated by enzyme histochemical technique. Scand J Dent Res. 1976;84(1):29-36. [Crossref]  [PubMed] 
  32. Rölling I, Thylstrup A. A 3-year clinical follow-up study of pulpotomized primary molars treated with the formocresol technique. Scand J Dent Res. 1975;83(2):47-53. [Crossref]  [PubMed] 

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