Turkiye Klinikleri Journal of Dental Sciences

.: REVIEW
Süt İkinci Azı Hipomineralizasyonu ve Klinik Önemi
Hypomineralized Second Primary Molars and its Clinical Implications
Elif BALLIKAYAa, Gizem ERBAŞ ÜNVERDİa, Zafer Cavit ÇEHRELİa
aHacettepe Üniversitesi Diş Hekimliği Fakültesi, Çocuk Diş Hekimliği ABD, Ankara, TÜRKİYE
Turkiye Klinikleri J Dental Sci. 2021;27(1):108-16
doi: 10.5336/dentalsci.2020-74182
Article Language: TR
Full Text
ÖZET
Diş çürüğü ve mine bozuklukları, çocuklarda çok yaygındır. Mine hipomineralizasyonu, çürük gelişimini ve çürüğün şiddetini artırabilen mine bozukluklarından biridir. Süt ikinci azı hipomineralizasyonu, minenin gelişimsel bir bozukluğu olmasının yanında büyük azı kesici hipomineralizasyonu (BKH) ile benzer klinik özelliklere sahiptir. SAH, klinik olarak 1-4 adet süt 2. azı dişi etkileyebilen, minede tipik olarak sarı-kahverengi renklenme ve belirgin bir opasite olarak tanımlanmaktadır. Süt 2. azılarda gözlenen, sınırları belirgin hipomineralizasyon varlığının, daimî dişlerde BKH görülmesinin bir işareti olabileceği bildirilmiştir. Diş sert dokularında meydana gelebilecek hızlı yıkımların, akut semptomların ve tekrarlayan tedavilerin önlenmesi açısından hipomineralizasyonun erken teşhis edilmesi önemlidir. Süt ve daimî dişlerde hipomineralizasyon varlığı; diş çürüğü, hassasiyet, ağrı, estetik kaygı ve diş yüzeyi kaybına neden olarak, çocuğun yaşam kalitesini olumsuz yönde etkileyebilir. Mine hipomineralizasyonlu tüm dişlerin tedavi yaklaşımında öncelikli olarak diş çürüğünün oluşumu önlenmelidir. Süt ikinci azı hipomineralizasyonu varlığı BKH'ye işaret edebileceğinden, veliyi konu hakkında bilgilendirmek, hijyen ve beslenme eğitimi vermek ve özellikle daimî 1. azıların sürme döneminde hastaları sık kontrollere çağırmak gerekmektedir. Bu tür dişlerin tedavi yaklaşımında etkilenen dişlerin tipi, defektlerin büyüklüğü ve şiddeti, diş yüzeyi kaybı ve ilişkili semptomlara bağlı olarak kısa ve uzun dönem tedavi planları gerektiren birçok restoratif yaklaşım bulunmaktadır. Bu kısa literatür derlemesinde, Süt ikinci azı hipomineralizasyonunun karakteristik özellikleri, görülme sıklığı, etiyolojisi, tanı kriterleri ve ayırıcı tanısı, klinik önemi ve tedavi yaklaşımı mevcut literatür ışığında değerlendirilecektir.

Anahtar Kelimeler: Süt dişi, mine hipomineralizasyonu, etiyoloji, ayırıcı tanı, hastalık yönetimi
ABSTRACT
Dental caries and enamel defects are very common among children. Hypomineralization is one of the enamel defects that can increase caries experience and severity. Hypomineralization of second primary molars (HSPM) a developmental defect of dental enamel and has similar clinical features with molar incisor hypomineralization (MIH). HPSM typically present as white, yellow or brown demarcated opacities in the enamel, affecting one to four primary second molars. The presence of demarcated molars hypomineralization of second primary molars has been cited as a predictor of molar incisor hypomineralization. Early diagnosis is essential to prevent rapid breakdown of tooth structure, acute symptoms and repeated treatments. Hypomineralization in the primary and permanent dentition can result in dental caries, hypersensitivity, pain, esthetic concerns, and tooth surface loss, therefore, affecting the child's quality of life. The prevention of dental caries is essential in the management of all patients with hypomineralized enamel. The presence of HSPM can be considered as a predictor of MIH, indicating the need for informing the parents, managing the oral hygiene and diet, control the patients regularly regarding MIH especially during the eruption of the first permanent molars. Many restorative techniques for the management of such teeth are available that might require short and long management treatment plans depending on the type of teeth affected, extent and severity of defects, tooth surface loss and associated symptoms. In this mini-review, the characteristic features, prevalence, etiology, diagnostic criteria, differential diagnosis, clinical importance and treatment approach of hypomineralization of second primary molars will be reviewed in the light of the current literature.

Keywords: Deciduous tooth, dental enamel hypoplasia, etiology, differential diagnosis, disease management
REFERENCES:
  1. Simmer JP, Hu JC. Dental enamel formation and its impact on clinical dentistry. J Dent Educ. 2001;65(9):896-905.[Crossref] [PubMed] 
  2. Weerheijm KL, Jälevik B, Alaluusua S. Molar-incisor hypomineralisation. Caries Res. 2001;35(5):390-1.[Crossref] [PubMed] 
  3. Fearne J, Anderson P, Davis GR. 3D X-ray microscopic study of the extent of variations in enamel density in first permanent molars with idiopathic enamel hypomineralisation. Br Dent J. 2004;22;196(10):634-8; discussion 625.[Crossref] [PubMed] 
  4. Jälevik B, Norén JG. Enamel hypomineralization of permanent first molars: a morphological study and survey of possible aetiological factors. Int J Paediatr Dent. 2000;10(4):278-89.[Crossref] [PubMed] 
  5. Beentjes VE, Weerheijm KL, Groen HJ. Factors involved in the aetiology of molar-incisor hypomineralisation (MIH). Eur J Paediatr Dent. 2002;3(1):9-13.[PubMed] 
  6. da Silva Figueiredo Sé MJ, Ribeiro APD, Dos Santos-Pinto LAM, de Cassia Loiola Cordeiro R, Cabral RN, et al. Are hypomineralized primary molars and canines associated with molar-incisor hypomineralization? Pediatr Dent. 2017;1;39(7):445-9.[PubMed] 
  7. Weerheijm KL, Duggal M, Mejàre I, Papagiannoulis L, Koch G, Martens LC, et al. Judgement criteria for molar incisor hypomineralisation (MIH) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003. Eur J Paediatr Dent. 2003;4(3):110-3.[PubMed] 
  8. Jälevik B, Klingberg GA. Dental treatment, dental fear and behaviour management problems in children with severe enamel hypomineralization of their permanent first molars. Int J Paediatr Dent. 2002;12(1):24-32.[Crossref] [PubMed] 
  9. Elfrink ME, Schuller AA, Weerheijm KL, Veerkamp JS. Hypomineralized second primary molars: prevalence data in Dutch 5-year-olds. Caries Res. 2008;42(4):282-5.[Crossref] [PubMed] 
  10. Jälevik B, Odelius H, Dietz W, Norén J. Secondary ion mass spectrometry and X-ray microanalysis of hypomineralized enamel in human permanent first molars. Archives of oral biology. 2001;46(3):239-47.[Crossref] 
  11. Farah RA, Monk BC, Swain MV, Drummond BK. Protein content of molar-incisor hypomineralisation enamel. J Dent. 2010;38(7):591-6.[Crossref] [PubMed] 
  12. Fagrell TG, Dietz W, Jälevik B, Norén JG. Chemical, mechanical and morphological properties of hypomineralized enamel of permanent first molars. Acta Odontol Scand. 2010;68(4):215-22.[Crossref] [PubMed] 
  13. Turner EG, Dean JA. Development and morphology of the primary teeth. In: Jones JE, Vinson LQA, eds. Dentistry for the Child and Adolescent. 10th ed. St. Louis: Elsevier; 2016. p.80-6.[Crossref] [PMC] 
  14. Ghanim AM, Morgan MV, Mari-o RJ, Bailey DL, Manton DJ. Risk factors of hypomineralised second primary molars in a group of Iraqi schoolchildren. Eur Arch Paediatr Dent. 2012;13(3):111-8.[Crossref] [PubMed] 
  15. Silva MJ, Scurrah KJ, Craig JM, Manton DJ, Kilpatrick N. Etiology of molar incisor hypomineralization - a systematic review. Community Dent Oral Epidemiol. 2016;44(4):342-53.[Crossref] [PubMed] 
  16. Vieira AR, Kup E. On the etiology of molar-incisor hypomineralization. Caries Res. 2016;50(2):166-9.[Crossref] [PubMed] 
  17. Lopes-Fatturi A, Menezes JVNB, Fraiz FC, Assunção LRDS, de Souza JF. Systemic exposures associated with hypomineralized primary second molars. Pediatr Dent. 2019;15;41(5):364-70.[PubMed] 
  18. Chowdhury IG, Bromage TG. Effects of fetal exposure to nicotine on dental development of the laboratory rat. Anat Rec. 2000;1;258(4):397-405.[Crossref] [PubMed] 
  19. Erin L, Gross Nowak AJ. Conception to age three. In: John R, Christensen Tad R, Mabry Janice A. Townsend Wells MH, eds. Pediatric Dentistry Infancy Through Adolescence. 8th ed. Philadelphia: Elsevier; 2018. p.586-87.
  20. Elfrink ME, ten Cate JM, Jaddoe VW, Hofman A, Moll HA, Veerkamp JS, et al. Deciduous molar hypomineralization and molar incisor hypomineralization. J Dent Res. 2012;91(6):551-5.[Crossref] [PubMed] 
  21. Ghanim A, Manton D, Mari-o R, Morgan M, Bailey D. Prevalence of demarcated hypomineralisation defects in second primary molars in Iraqi children. Int J Paediatr Dent. 2013;23(1):48-55.[Crossref] [PubMed] 
  22. Lygidakis NA, Wong F, Jälevik B, Vierrou AM, Alaluusua S, Espelid I, et al. Best clinical practice Guidance for clinicians dealing with children presenting with Molar-Incisor-Hypomineralisation (MIH): an EAPD policy document. Eur Arch Paediatr Dent. 2010;11(2):75-81.[Crossref] [PubMed] 
  23. Elfrink ME, Veerkamp JS, Kalsbeek H. Caries pattern in primary molars in Dutch 5-year-old children. Eur Arch Paediatr Dent. 2006;7(4):236-40.[Crossref] [PubMed] 
  24. Elfrink ME, Schuller AA, Veerkamp JS, Poorterman JH, Moll HA, ten Cate BJ, et al. Factors increasing the caries risk of second primary molars in 5-year-old Dutch children. Int J Paediatr Dent. 2010;20(2):151-7.[Crossref] [PubMed] 
  25. Lunardelli SE, Peres MA. Prevalence and distribution of developmental enamel defects in the primary dentition of pre-school children. Braz Oral Res. 2005;19(2):144-9.[Crossref] [PubMed] 
  26. Clarkson J, O'Mullane D. A modified DDE Index for use in epidemiological studies of enamel defects. J Dent Res. 1989;68(3):445-50.[Crossref] [PubMed] 
  27. Elfrink ME, Veerkamp JS, Aartman IH, Moll HA, Ten Cate JM. Validity of scoring caries and primary molar hypomineralization (DMH) on intraoral photographs. Eur Arch Paediatr Dent. 2009;10 Suppl 1:5-10.[Crossref] [PubMed] 
  28. Jälevik B. Prevalence and diagnosis of Molar-Incisor- Hypomineralisation (MIH): a systematic review. Eur Arch Paediatr Dent. 2010;11(2):59-64.[Crossref] [PubMed] 
  29. Elfrink ME, Ghanim A, Manton DJ, Weerheijm KL. Standardised studies on Molar Incisor Hypomineralisation (MIH) and Hypomineralised Second Primary Molars (HSPM): a need. Eur Arch Paediatr Dent. 2015;16(3):247-55.[Crossref] [PubMed] 
  30. Ghanim A, Elfrink M, Weerheijm K, Mari-o R, Manton D. A practical method for use in epidemiological studies on enamel hypomineralisation. Eur Arch Paediatr Dent. 2015;16(3):235-46.[Crossref] [PubMed] [PMC] 
  31. Jälevik B, Klingberg G, Barregård L, Norén JG. The prevalence of demarcated opacities in permanent first molars in a group of Swedish children. Acta Odontol Scand. 2001;59(5):255-60.[Crossref] [PubMed] 
  32. Calderara PC, Gerthoux PM, Mocarelli P, Lukinmaa PL, Tramacere PL, Alaluusua S, et al. The prevalence of Molar Incisor Hypomineralisation (MIH) in a group of Italian school children. Eur J Paediatr Dent. 2005;6(2):79-83.[PubMed] 
  33. Jasulaityte L, Veerkamp JS, Weerheijm KL. Molar incisor hypomineralization: review and prevalence data from the study of primary school children in Kaunas/Lithuania. Eur Arch Paediatr Dent. 2007;8(2):87-94.[Crossref] [PubMed] 
  34. Owen ML, Ghanim A, Elsby D, Manton DJ. Hypomineralized second primary molars: prevalence, defect characteristics and relationship with dental caries in Melbourne preschool children. Aust Dent J. 2018;63(1):72-80.[Crossref] [PubMed] 
  35. A review of the developmental defects of enamel index (DDE Index). Commission on Oral Health, Research & Epidemiology. Report of an FDI Working Group. Int Dent J. 1992;42(6):411-26.[PubMed] 
  36. Crawford PJ, Aldred M, Bloch-Zupan A. Amelogenesis imperfecta. Orphanet J Rare Dis. 2007;4;2:17.[Crossref] [PubMed] [PMC] 
  37. Lo EC, Zheng CG, King NM. Relationship between the presence of demarcated opacities and hypoplasia in permanent teeth and caries in their primary predecessors. Caries Res. 2003;37(6):456-61.[Crossref] [PubMed] 
  38. Broadbent JM, Thomson WM, Williams SM. Does caries in primary teeth predict enamel defects in permanent teeth? A longitudinal study. J Dent Res. 2005;84(3):260-4.[Crossref] [PubMed] 
  39. Weerheijm KL. Molar incisor hypomineralization (MIH): clinical presentation, aetiology and management. Dent Update. 2004;31(1):9-12.[Crossref] [PubMed] 
  40. Seow WK. Clinical diagnosis of enamel defects: pitfalls and practical guidelines. Int Dent J. 1997;47(3):173-82.[Crossref] [PubMed] 
  41. Weerheijm KL. Molar incisor hypomineralisation (MIH). Eur J Paediatr Dent. 2003;4(3):114-20.[PubMed] 
  42. Rodd HD, Boissonade FM, Day PF. Pulpal status of hypomineralized permanent molars. Pediatr Dent. 2007;29(6):514-20.[PubMed] 
  43. Fayle SA. Molar incisor hypomineralisation: restorative management. Eur J Paediatr Dent. 2003;4(3):121-6.[PubMed] 
  44. Azarpazhooh A, Limeback H. Clinical efficacy of casein derivatives: a systematic review of the literature. J Am Dent Assoc. 2008;139(7):915-24.[Crossref] [PubMed] 
  45. Pasini M, Giuca MR, Scatena M, Gatto R, Caruso S. Molar incisor hypomineralization treatment with casein phosphopeptide and amorphous calcium phosphate in children. Minerva Stomatol. 2018;67(1):20-5.[PubMed] 
  46. Lygidakis NN, Chatzidimitriou K, Lygidakis NA. The Use of Fissure Sealants in MIH-Affected Posterior Teeth. Molar Incisor Hypomineralization ed. Springer; 2020. p.127-35.[Crossref] 
  47. Wright JT. Diagnosis and treatment of molar-incisor hypomineralization. Handbook of Clinical Techniques in Pediatric Dentistry. 2015.[Crossref] [PMC] 
  48. William V, Messer LB, Burrow MF. Molar incisor hypomineralization: review and recommendations for clinical management. Pediatr Dent. 2006;28(3):224-32.[PubMed] 
  49. Nazzal H, Duggal MS. Restorative management of dental enamel defects in the primary dentition. Clin Dent Rev. 2019;3(1):1-7.[Link] 

.: Up To Date

Login



Contact


Ortadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş.

.: Address

Turkocagi Caddesi No:30 06520 Balgat / ANKARA
Phone: +90 312 286 56 56
Fax: +90 312 220 04 70
E-mail: info@turkiyeklinikleri.com

.: Manuscript Editing Department

Phone: +90 312 286 56 56/ 2
E-mail: yaziisleri@turkiyeklinikleri.com

.: English Language Redaction

Phone: +90 312 286 56 56/ 145
E-mail: tkyayindestek@turkiyeklinikleri.com

.: Marketing Sales-Project Department

Phone: +90 312 286 56 56/ 142
E-mail: reklam@turkiyeklinikleri.com

.: Subscription and Public Relations Department

Phone: +90 312 286 56 56/ 118
E-mail: abone@turkiyeklinikleri.com

.: Customer Services

Phone: +90 312 286 56 56/ 118
E-mail: satisdestek@turkiyeklinikleri.com

1. TERMS OF USE

1.1. To use the web pages with http://www.turkiyeklinikleri.com domain name or the websites reached through the sub domain names attached to the domain name (They will be collectively referred as "SITE"), please read the conditions below. If you do not accept these terms, please cease to use the "SITE." "SITE" owner reserves the right to change the information on the website, forms, contents, the "SITE," "SITE" terms of use anytime they want.

1.2. The owner of the "SITE" is Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. (From now on it is going to be referred as "Turkiye Klinikleri", shortly) and it resides at Turkocagi cad. No:30, 06520 Balgat Ankara. The services in the "SITE" are provided by "Turkiye Klinikleri."

1.3. Anyone accessing the "SITE" with or without a fee whether they are a natural person or a legal identity is considered to agree these terms of use. In this contract hereby, "Turkiye Klinikleri" may change the stated terms anytime. These changes will be published in the "SITE" periodically and they will be valid when they are published. Any natural person or legal identity benefiting from and reaching to the "SITE" are considered to be agreed to any change on hereby contract terms done by "Turkiye Klinikleri."

1.4. The "Terms of Use" hereby is published in the website with the last change on March 30th 2014 and the "SITE" is activated by enabling the access to everyone. The "Terms of Use" hereby is also a part of the any "USER Contract" was and/or will be done with the users using "Turkiye Klinikleri" services with or without a fee an inseparable.

2. DEFINITIONS

2.1. "SITE": A website offering different kind of services and context with a certain frame determined by "Turkiye Klinikleri" and it is accessible on-line on http://www.turkiyeklinikleri.com domain name and/or subdomains connected to the domain name.

2.2. USER: A natural person or a legal identity accessing to the "SITE" through online settings.

2.3. LINK: A link enabling to access to another website through the "SITE", the files, the context or through another website to the "SITE", the files and the context.

2.4. CONTEXT: Any visual, literary and auditory images published in the "Turkiye Klinikleri", "SITE" and/or any website or any accessible information, file, picture, number/figures, price, etc.

2.5. "USER CONTRACT": An electronically signed contract between a natural or a legal identity benefiting from special services "Turkiye Klinikleri" will provide and "Turkiye Klinikleri".

3. SCOPE OF THE SERVICES

3.1. "Turkiye Klinikleri" is completely free to determine the scope and quality of the services via the "SITE".

3.2. To benefit the services of "Turkiye Klinikleri" "SITE", the "USER" must deliver the features that will be specified by "Turkiye Klinikleri". "Turkiye Klinikleri" may change this necessity any time single-sided.

3.3. Not for a limited number, the services "Turkiye Klinikleri" will provide through the "SITE" for a certain price or for free are;

- Providing scientific articles, books and informative publications for health industry.

- Providing structural, statistical and editorial support to article preparation stage for scientific journals.

4. GENERAL PROVISIONS

4.1. "Turkiye Klinikleri" is completely free to determine which of the services and contents provided in the "SITE" will be charged.

4.2. People benefiting from the services provided by "Turkiye Klinikleri" and using the website can use the "SITE" only according to the law and only for personal reasons. Users have the criminal and civil liability for every process and action they take in the "SITE". Every USER agrees, declares and undertakes that they will not proceed by any function or action infringement of rights of "Turkiye Klinikleri"s and/or other third parties', they are the exclusive right holder on usage, processing, storage, made public and revealing any written, visual or auditory information reported to Turkiye Klinikleri" and/or "SITE" to the third parties. "USER" agrees and undertakes that s/he will not duplicate, copy, distribute, process, the pictures, text, visual and auditory images, video clips, files, databases, catalogs and lists within the "SITE", s/he will not be using these actions or with other ways to compete with "Turkiye Klinikleri", directly or indirectly.

4.3. The services provided and the context published within the "SITE" by third parties is not under the responsibility of "Turkiye Klinikleri", institutions collaborated with "Turkiye Klinikleri", "Turkiye Klinikleri" employee and directors, "Turkiye Klinikleri" authorized salespeople. Commitment to accuracy and legality of the published information, context, visual and auditory images provided by any third party are under the full responsibility of the third party. "Turkiye Klinikleri" does not promise and guarantee the safety, accuracy and legality of the services and context provided by a third party.

4.4. "USER"s cannot act against "Turkiye Klinikleri", other "USER"s and third parties by using the "SITE". "Turkiye Klinikleri" has no direct and/or indirect responsibility for any damage a third party suffered or will suffer regarding "USER"s actions on the "SITE" against the rules of the hereby "Terms of Use" and the law.

4.5. "USER"s accept and undertake that the information and context they provided to the "SITE" are accurate and legal. "Turkiye Klinikleri" is not liable and responsible for promising and guaranteeing the verification of the information and context transmitted to "Turkiye Klinikleri" by the "USER"s, or uploaded, changed and provided through the "SITE" by them and whether these information are safe, accurate and legal.

4.6. "USER"s agree and undertake that they will not perform any action leading to unfair competition, weakening the personal and commercial credit of "Turkiye Klinikleri" and a third party,  encroaching and attacking on personal rights within the "SITE" in accordance with the Turkish Commercial Code Law.

4.7. "Turkiye Klinikleri" reserves the right to change the services and the context within the "SITE"  anytime. "Turkiye Klinikleri" may use this right without any notification and timelessly. "USER"s have to make the changes and/or corrections "Turkiye Klinikleri" required immediately. Any changes and/or corrections that are required by "Turkiye Klinikleri", may be made by "Turkiye Klinikleri" when needed. Any harm, criminal and civil liability resulted or will result from changes and/or corrections required by "Turkiye Klinikleri" and were not made on time by the "USER"s belongs completely to the users.

4.8. "Turkiye Klinikleri" may give links through the "SITE" to other websites and/or "CONTEXT"s and/or folders that are outside of their control and owned and run by third parties. These links are provided for ease of reference only and do not hold qualification for support the respective web SITE or the admin or declaration or guarantee for the information inside. "Turkiye Klinikleri" does not hold any responsibility over the web-sites connected through the links on the "SITE", folders and context, the services or products on the websites provided through these links or their context.

4.9. "Turkiye Klinikleri" may use the information provided to them by the "USERS" through the "SITE" in line with the terms of the "PRIVACY POLICY" and "USER CONTRACT". It may process the information or classify and save them on a database. "Turkiye Klinikleri" may also use the USER's or visitor's identity, address, e-mail address, phone number, IP number, which sections of the "SITE" they visited, domain type, browser type, date and time information to provide statistical evaluation and customized services.

5. PROPRIETARY RIGHTS

5.1. The information accessed through this "SITE" or provided by the users legally and all the elements (including but not limited to design, text, image, html code and other codes) of the "SITE" (all of them will be called as studies tied to "Turkiye Klinikleri"s copyrights) belongs to "Turkiye Klinikleri". Users do not have the right to resell, process, share, distribute, display or give someone permission to access or to use the "Turkiye Klinikleri" services, "Turkiye Klinikleri" information and the products under copyright protection by "Turkiye Klinikleri". Within hereby "Terms of Use" unless explicitly permitted by "Turkiye Klinikleri" nobody can reproduce, process, distribute or produce or prepare any study from those under "Turkiye Klinikleri" copyright protection.

5.2. Within hereby "Terms of Use", "Turkiye Klinikleri" reserves the rights for "Turkiye Klinikleri" services, "Turkiye Klinikleri" information, the products associated with "Turkiye Klinikleri" copyrights, "Turkiye Klinikleri" trademarks, "Turkiye Klinikleri" trade looks or its all rights for other entity and information it has through this website unless it is explicitly authorized by "Turkiye Klinikleri".

6. CHANGES IN THE TERMS OF USE

"Turkiye Klinikleri" in its sole discretion may change the hereby "Terms of Use" anytime announcing within the "SITE". The changed terms of the hereby "Terms of Use" will become valid when they are announced. Hereby "Terms of Use" cannot be changed by unilateral declarations of users.

7. FORCE MAJEURE

"Turkiye Klinikleri" is not responsible for executing late or never of this hereby "Terms of Use", privacy policy and "USER Contract" in any situation legally taken into account as force majeure. Being late or failure of performance or non-defaulting of this and similar cases like this will not be the case from the viewpoint of "Turkiye Klinikleri", and "Turkiye Klinikleri" will not have any damage liability for these situations. "Force majeure" term will be regarded as outside of the concerned party's reasonable control and any situation that "Turkiye Klinikleri" cannot prevent even though it shows due diligence. Also, force majeure situations include but not limited to natural disasters, rebellion, war, strike, communication problems, infrastructure and internet failure, power cut and bad weather conditions.

8. LAW AND AUTHORISATION TO FOLLOW

Turkish Law will be applied in practicing, interpreting the hereby "Terms of Use" and managing the emerging legal relationships within this "Terms of Use" in case of finding element of foreignness, except for the rules of Turkish conflict of laws. Ankara Courts and Enforcement Offices are entitled in any controversy happened or may happen due to hereby contract.

9. CLOSING AND AGREEMENT

Hereby "Terms of Use" come into force when announced in the "SITE" by "Turkiye Klinikleri". The users are regarded to agree to hereby contract terms by using the "SITE". "Turkiye Klinikleri" may change the contract terms and the changes will be come into force by specifying the version number and the date of change on time it is published in the "SITE".

 

30.03.2014

Privacy Policy

We recommend you to read the terms of use below before you visit our website. In case you agree these terms, following our rules will be to your favor. Please read our Terms of Use thoroughly.

www.turkiyeklinikleri.com website belongs to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. and is designed in order to inform physicians in the field of health

www.turkiyeklinikleri.com cannot reach to user’s identity, address, service providers or other information. The users may send this information to the website through forms if they would like to. However, www.turkiyeklinikleri.com may collect your hardware and software information. The information consists of your IP address, browser type, operating system, domain name, access time, and related websites. www.turkiyeklinikleri.com cannot sell the provided user information (your name, e-mail address, home and work address, phone number) to the third parties, publish it publicly, or keep it in the website. Gathered information has a directing feature to be a source for the website’s visitor profile, reporting and promotion of the services.

www.turkiyeklinikleri.com uses the taken information:

-To enhance, improve and maintain the quality of the website

-To generate visitor’s profile and statistical data

-To determine the tendency of the visitors on using our website

-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

info@turkiyeklinikleri.com