Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Volumetric Comparison of New Bone Formation in Sinus Floor Augmentation Using Allografts with/without Platelet-Rich Fibrin Cohort Research (Retrospective)
Trombositten Zengin Fibrin İçeren/İçermeyen Allogreftler ile Sinüs Tabanı Ögmentasyonunda Yeni Kemik Oluşumunun Hacimsel Karşılaştırması Kohort Araştırması (Retrospektif)
Ömür DERECİa , Nesrin SARUHANa , Görkem TEKİNa , Mehmet UĞURLUb
aDepartment of Oral and Maxillofacial Surgery, Eskişehir Osmangazi University Faculty of Dentistry, Eskişehir, Türkiye
bDepartment of Orthodontics, Eskişehir Osmangazi University Faculty of Dentistry, Eskişehir, Türkiye
Turkiye Klinikleri J Dental Sci. 2023;29(3):409-18
doi: 10.5336/dentalsci.2023-96060
Article Language: EN
Full Text
ABSTRACT
 Objective: To compare the new bone regeneration potential of bone allograft and bone allograft and platelet-rich fibrin (PRF) mixture with volumetric analysis in sinus floor augmentation. Material and Methods: Patients with chronic metabolic disease, smoking and not paying much attention to oral care were excluded from the study. Patients were allocated into two groups. In Group 1, sinus floor augmentations were performed with bone allografts alone and in Group 2, a mixture of bone allograft and PRF was used as sinus bone graft. Graft volume was determined by subtracting the preoperative total sinus volume from the postoperative total sinus volume using the Dolphin programme. Residual and post-operative ridge heights were measured by Simplant software programme on the mid-sagittal section of pre-operative and post-operative cone beam computed tomography (CBCT) images. The mean Hounsfield unit (HU) values were also measured in sagittal sections of CBCT data. Results: Thirty patients with 43 sinus floor augmentations were included in the study. The new bone formation and mean HU value in Group 2 were significantly higher than in Group 1 (p0.05). Conclusion: PRF and bone allograft combination may enhance higher levels of new bone formation than bone allograft alone for sinus floor augmentation. The mixture of bone allograft and PRF provides new bone regeneration of sinus floor augmentation regardless of the residual ridge height.

Keywords: Allografts; dental implants; sinus floor augmentation; platelet-rich fibrin
ÖZET
 Amaç: Sinüs taban ögmentasyonunda kemik allogrefti ile kemik allogreft ve trombositten zengin fibrin [platelet-rich fibrin (PRF)] karışımının yeni kemik rejenerasyon potansiyelinin volümetrik analizle karşılaştırılmasıdır. Gereç ve Yöntemler: Kronik metabolik hastalığı olan, sigara içen ve ağız bakımına fazla dikkat etmeyen hastalar çalışma dışı bırakıldı. Hastalar iki gruba ayrıldı. Grup 1'de sinüs tabanı ögmentasyonları sadece kemik allogreftleri ile yapıldı ve Grup 2'deki sinüs ögmentasyonunda kemik grefti olarak kemik allogreft ve PRF karışımı kullanıldı. Greft hacmi Dolphin programı kullanılarak ameliyat öncesi tam sinüs hacminin, ameliyat sonrası tam sinüs hacminden çıkarılmasıyla belirlendi. Ameliyat öncesi ve sonrası konik ışınlı bilgisayarlı tomografi (KIBT) görüntülerinin orta sagittal kesitlerinde rezidüel kemik ve ameliyat sonrası oluşan yeni kemik yükseklikleri Simplant yazılım programı ile ölçüldü. Ortalama ''Hounsfield unit (HU)'' değerleri, KIBT verilerinin sagittal kesitlerinde de ölçüldü. Bulgular: Kırk üç sinüs tabanı ögmentasyonu yapılan 30 hasta çalışmaya dâhil edildi. Grup 2'de yeni kemik oluşumu ve ortalama HU değeri Grup 1'e göre anlamlı olarak yüksek bulundu (p0,05). Sonuç: PRF ve allogreft karışımı, sinüs tabanı ögmentasyonu için tek başına kemik allogreftinden daha yüksek seviyelerde yeni kemik oluşumunu artırabilir. Allogreft ve PRF karışımı, rezidüel sırt yüksekliğinden bağımsız olarak sinüs tabanı ögmentasyonunda yeni kemik rejenerasyonu sağlar.

Anahtar Kelimeler: Allogreftler; diş implantları; sinüs tabanı yükseltmesi; trombositten zengin fibrin
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