Turkiye Klinikleri Journal of Dental Sciences

.: ORIGINAL RESEARCH
Ağız Gargaralarının Rezin Bazlı CAD/CAM Blokların Renk Stabilitesine Etkisinin İn Vitro İncelenmesi
In Vitro Investigation of the Effect of Mouthwashes on Color Stability of Resin Based CAD/CAM Blocks
Melis BAYSAL CANYURTa, Elif Aybala OKTAYa, Numan AYDINa, Serpil KARAOĞLANOĞLUa
aSağlık Bilimleri Üniversitesi Gülhane Diş Hekimliği Fakültesi, Restoratif Diş Tedavisi ABD, Ankara, TÜRKİYE
Turkiye Klinikleri J Dental Sci. 2022;28(1):181-7
doi: 10.5336/dentalsci.2021-83507
Article Language: TR
Full Text
ÖZET
Amaç: Bu çalışmanın amacı, farklı gargaraların rezin bazlı bilgisayar destekli tasarım ve bilgisayar destekli üretim [computer-aided design/computer-aided manufacturing (CAD/CAM)] bloklarının renk stabilitesine etkisini incelemektir. Gereç ve Yöntemler: Çalışmada, rezin bazlı CAD/CAM bloklardan (Vita Enamic, Brilliant Crios, Grandio Blocs) 1,5×7×12 mm boyutlarında örnekler hazırlandı. CAD/CAM örneklerin zamana bağlı renk değişimini simüle etmek için her gün 1 dk süreyle farklı gargaralarda (Listerine Cool Mint, Listerine Zero, Colgate Plax, Sensodyne) bekletilip, tekrar yapay tükürük içerisine konuldu. Örneklerin renk değişimi spektrofotometre cihazı ile 7, 14 ve 30. günlerde ölçüldü. Renk değişim değerlerinin (ΔE00), tek yönlü varyans analizi ve Tukey analizi kullanılarak istatistiksel analizi yapıldı (p0,05). Alkollü (Listerine Cool Mint) ve alkolsüz gargaralar (Listerine Zero, Colgate Plax ve Sensodyne), 30 gün sonunda Vita Enamic ve Brilliant Crios blokları üzerinde algılanabilirlik eşiği [perceptibility threshold (PT)] değerinin (ΔE00: 0,8) altında renk değişikliğine neden olurken, Grandio Blocs örneklerinde PT değerinin üzerinde değerlere neden olduğu görüldü. Klorheksidin içerikli gargara (Kloroben), 30 gün sonunda tüm bloklarda en fazla (Vita Enamic ΔE00: 0,81, Brilliant Crios ΔE00: 0,84 ve Grandio Blocs ΔE00: 1,05) renk değişikliği gösterdi. Gargaraların rezin bazlı CAD/CAM bloklar üzerindeki renk değişikliği, kabul edilebilirlik eşiği değerini (ΔE00≤1,8) geçmedi. Sonuç: Rezin içerikli CAD/CAM restorasyonu bulunan bireylerin kullandıkları gargaraların kullanım süresi ve içerikleri, restorasyonların uzun dönem renk stabilitesi için önemlidir.

Anahtar Kelimeler: Ağız gargarası; CAD/CAM blok; renk değişikliği
ABSTRACT
Objective: The aim of this study is to examine the effect of different mouthwashes on the color stability of resin computer-aided design/computer-aided manufacturing (CAD/CAM) blocks. Material and Methods: In the study, samples of 1.5×7×12 mm were prepared from resin-based CAD/CAM blocks (Vita Enamic, Brilliant Crios, Grandio Blocs). In order to simulate the time-dependent color change of the CAD/CAM samples, they were kept in mouthwash (Listerine Cool Mint, Listerine Zero, Colgate Plax, Sensodyne) for one minute each day and put back into artificial saliva. Color changes of the samples were measured with a spectrophotometer device on 7th, 14th and 30th days. Statistical analysis of the values of color change (ΔE00) was performed using one-way variance analysis and Tukey analysis. Results: Color changes of CAD/CAM blocks did not show statistically significant difference compared to the control group (p>0.05). Alcoholic (Listerine Cool Mint) and non-alcoholic (Listerine Zero, Colgate Plax and Sensodyne) mouthwashes were found to be below the perceptibility threshold (PT) value (ΔE00: 0.8), while the color change on Vita Enamic and Brilliant Crios from the blocks at the end of 30 days was above the PT value in the Grandio Blocs. Chlorhexidine-containing mouthwash (Kloroben) showed the most color change in all blocks (Vita Enamic ΔE00: 0.81, Brilliant Crios ΔE00: 0.84 and Grandio Blocs ΔE00: 1.05) at the end of 30 days. The color change of the mouthwashes on the resin-based CAD/CAM blocks did not exceed the acceptability threshold value (ΔE00≤1.8). Conclusion: The duration of use and contents of the mouthwash used by individuals with resin-based CAD/CAM restorations are important for the color stability of the restorations.

Keywords: Mouthwash; CAD/CAM block; color change
REFERENCES:
  1. Sarıkaya İ, Güleç C. Estetik restoratif CAD/CAM materyallerin translüsensi ve renk stabilitesinin değerlendirilmesi [Evaluation of translucency and color stability of esthetic CAD/CAM restorative materials]. J Dent Fac Atatürk Uni. 2018;28(3):365-70. [Crossref] 
  2. Awada A, Nathanson D. Mechanical properties of resin-ceramic CAD/CAM restorative materials. J Prosthet Dent. 2015;114(4):587-93. [Crossref]  [PubMed] 
  3. Coldea A, Swain MV, Thiel N. Mechanical properties of polymer-infiltrated-ceramic- network materials. Dent Mater. 2013;29(4):419-26. [Crossref]  [PubMed] 
  4. Rusin RP. Properties and applications of a new composite block for CAD/CAM. Compend Contin Educ Dent. 2001;22(6 Suppl):35-41. [PubMed] 
  5. Patel SB, Gordan VV, Barrett AA, Shen C. The effect of surface finishing and storage solutions on the color stability of resin-based composites. J Am Dent Assoc. 2004;135(5):587- 94. [Crossref]  [PubMed] 
  6. Aulitto L, Ramaglia L, Ciaglia RN, Sbordone L. [The use of antiseptic agents for the chemical control of dental plaque]. Minerva Stomatol. 1991;40(1-2):29-35. [PubMed] 
  7. DeVore LR. Antimicrobial mouthrinces: impact on dental hygiene. J Am Dent Assoc. 1994;125 Suppl 2:23S-8S. [Crossref]  [PubMed] 
  8. Parkinson CR, Hara AT, Nehme M, Lippert F, Zero DT. A randomised clinical evaluation of a fluoride mouthrinse and dentifrice in an in situ caries model. J Dent. 2018;70:59-66. [Crossref]  [PubMed] 
  9. Tartaglia GM, Tadakamadla SK, Connelly ST, Sforza C, Martín C. Adverse events associated with home use of mouthrinses: a systematic review. Ther Adv Drug Saf. 2019; 10:1-16. [Crossref]  [PubMed]  [PMC] 
  10. de Azevedo Miranda D, Dos Santos Bertoldo CE, Baggio Aguiar FH, Nunes Leite Lima DA, Lovadino JR. Effects of mouthwashes on Knoop hardness and surface roughness of dental composites after different immersion times. Braz Oral Res. 2011;25(2):168-73. [Crossref]  [PubMed] 
  11. Paravina RD, Pérez MM, Ghinea R. Acceptability and perceptibility thresholds in dentistry: a comprehensive review of clinical and research applications. J Esthet Restor Dent. 2019;31(2):103-12. [Crossref]  [PubMed] 
  12. Cavalcanti AN, Ogata Mitsui FH, Bovi Ambrosano GM, Mathias P, Marchi GM. Effect of different mouthrinses on Knoop hardness of a restorative composite. Am J Dent. 2005;18(6): 338-40. [PubMed] 
  13. Gürdal P, Akdeniz BG, Hakan Sen B. The effects of mouthrinses on microhardness and colour stability of aesthetic restorative materyals. J Oral Rehabil. 2002;29(9):895-901. [Crossref]  [PubMed] 
  14. Cal E, Güneri P, Kose T. Digital analysis of mouthrinses' staining characteristics on provisional acrylic resins. J Oral Rehabil. 2007; 34(4):297-303. [Crossref]  [PubMed] 
  15. Cengiz S, Yüzbaşioğlu E, Cengiz MI, Velioğlu N, Sevimli G. Color stability and surface roughness of a laboratory-processed composite resin as a function of mouthrinse. J Esthet Restor Dent. 2015;27(5):314-21. [Crossref]  [PubMed] 
  16. Sano Trauth KG, Terossi de Godoi AP, Colucci V, Milori Corona SA, Concepción Elizaur Benitez Catirse AB. The influence of mouthrinses and simulated toothbrushing on the surface roughness of a nanofilled composite resin. Braz Oral Res. 2012;26(3):209-14. [Crossref]  [PubMed] 
  17. Turgut S, Bagis B, Ayaz EA, Ulusoy KU, Altintas SH, Korkmaz FM, et al. Discoloration of provisional restorations after oral rinses. Int J Med Sci. 2013;10(11):1503-9. [Crossref]  [PubMed]  [PMC] 
  18. Arocha MA, Basilio J, Llopis J, Di Bella E, Roig M, Ardu S, et al. Colour stainability of indirect CAD-CAM processed composites vs. conventionally laboratory processed composites after immersion in staining solutions. J Dent. 2014;42(7):831-8. [Crossref]  [PubMed] 
  19. Zenthöfer A, Cabrera T, Corcodel N, Rammelsberg P, Hassel AJ. Comparison of the Easyshade compact and advance in vitro and in vivo. Clin Oral Investig. 2013;18(5):1473-9. [Crossref]  [PubMed] 
  20. Sharma G, Wu W, Dalal E. The CIEDE2000 color-difference formula: implementation notes, supplementary test data, and mathematical observations. Color Res Appl. 2005;30(1):21-30. [Crossref] 
  21. Gómez-Polo C, Portillo Mu-oz M, Cruz Lorenzo Luengo M, Vicente P, Galindo P, Casado AAM. Comparison of the CIELab and CIEDE2000 color difference formulas. J Prosthet Dent. 2016;115(1):65-70. [Crossref]  [PubMed] 
  22. Städtler P, Pabst MA. Chemische Degradation von 15 Komposits--eine SEM-Studie [Chemical degradation of 15 composites--an SEM study]. ZWR. 1991;100(5):309-12. German. [PubMed] 
  23. Asmussen E. Softening of BISGMA-based polymers by ethanol and by organic acids of plaque. Scand J Dent Res. 1984;92(3):257-61. [Crossref]  [PubMed] 
  24. Soygun K, Varol O, Ozer A, Bolayir G. Investigations on the effects of mouthrinses on the colour stability and surface roughness of different dental bioceramics. J Adv Prosthodont. 2017;9(3):200-7. [Crossref]  [PubMed]  [PMC] 
  25. El-Sayed ElEmbaby A. The effects of mouth rinses on the color stability of resin-based restorative materyals. J Esthet Restor Dent. 2014;26(4):264-71. [Crossref]  [PubMed] 
  26. Trauth KGS, de Godoi APT, Colucci V, Corona SAM, Catirse AB. The influence of mouthrin ses and simulated toothbrushing on the surface roughness of a nanofilled composite resin. Braz Oral Res. 2012;26(3):209-14. [Crossref]  [PubMed] 
  27. de Alencar E Silva Leite ML, da Cunha Medeiros E Silva FS, Meireles SS, Duarte RM, Andrade AKM. The effect of drinks on color stability and surface roughness of nanocomposites. Eur J Dent. 2014;8(3):330-6. [Crossref]  [PubMed]  [PMC] 
  28. Mainjot A, Dupont N, Oudkerk J, Dewael T, Sadoun M. From artisanal to CAD-CAM blocks: Atate of the art of indirect composites. J Dent Res. 2016;95(5):487-95. [Crossref]  [PubMed] 
  29. Belli R, Geinzer E, Muschweck A, Petschelt A, Lohbauer U. Mechanical fatigue degradation of ceramics versus resin composites for dental restorations. Dent Mater. 2014;30(4):424-32. [Crossref]  [PubMed] 
  30. Vasudeva G. Monomer systems for dental composites and their future: a rewiev. J Calif Dent Assoc. 2009;37(6):389-98. [PubMed] 
  31. Gajewski VES, Pfeifer CS, Froes-Salgado NR, Boaro LCC, Braga RR. Monomers used in resin composites: Degree of conversion, mechanical properties and water sorption/solubility. Braz Dent J. 2012;23(5):508-14. [Crossref]  [PubMed] 
  32. Stawarczyk B, Sener B, Trottmann A, Roos M, Ozcan M, Hämmerle CH. Discoloration of manually fabricated resins and industrially fabricated CAD/CAM blocks versus glass-ceramic: effect of storage media, duration, and subsequent polishing. Dent Mater J. 2012; 31(3):377-83. [Crossref]  [PubMed] 

.: Up To Date

Login



Contact


Ortadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş.

.: Address

Turkocagi Caddesi No:30 06520 Balgat / ANKARA
Phone: +90 312 286 56 56
Fax: +90 312 220 04 70
E-mail: info@turkiyeklinikleri.com

.: Manuscript Editing Department

Phone: +90 312 286 56 56/ 2
E-mail: yaziisleri@turkiyeklinikleri.com

.: English Language Redaction

Phone: +90 312 286 56 56/ 145
E-mail: tkyayindestek@turkiyeklinikleri.com

.: Marketing Sales-Project Department

Phone: +90 312 286 56 56/ 142
E-mail: reklam@turkiyeklinikleri.com

.: Subscription and Public Relations Department

Phone: +90 312 286 56 56/ 118
E-mail: abone@turkiyeklinikleri.com

.: Customer Services

Phone: +90 312 286 56 56/ 118
E-mail: satisdestek@turkiyeklinikleri.com

1. TERMS OF USE

1.1. To use the web pages with http://www.turkiyeklinikleri.com domain name or the websites reached through the sub domain names attached to the domain name (They will be collectively referred as "SITE"), please read the conditions below. If you do not accept these terms, please cease to use the "SITE." "SITE" owner reserves the right to change the information on the website, forms, contents, the "SITE," "SITE" terms of use anytime they want.

1.2. The owner of the "SITE" is Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. (From now on it is going to be referred as "Turkiye Klinikleri", shortly) and it resides at Turkocagi cad. No:30, 06520 Balgat Ankara. The services in the "SITE" are provided by "Turkiye Klinikleri."

1.3. Anyone accessing the "SITE" with or without a fee whether they are a natural person or a legal identity is considered to agree these terms of use. In this contract hereby, "Turkiye Klinikleri" may change the stated terms anytime. These changes will be published in the "SITE" periodically and they will be valid when they are published. Any natural person or legal identity benefiting from and reaching to the "SITE" are considered to be agreed to any change on hereby contract terms done by "Turkiye Klinikleri."

1.4. The "Terms of Use" hereby is published in the website with the last change on March 30th 2014 and the "SITE" is activated by enabling the access to everyone. The "Terms of Use" hereby is also a part of the any "USER Contract" was and/or will be done with the users using "Turkiye Klinikleri" services with or without a fee an inseparable.

2. DEFINITIONS

2.1. "SITE": A website offering different kind of services and context with a certain frame determined by "Turkiye Klinikleri" and it is accessible on-line on http://www.turkiyeklinikleri.com domain name and/or subdomains connected to the domain name.

2.2. USER: A natural person or a legal identity accessing to the "SITE" through online settings.

2.3. LINK: A link enabling to access to another website through the "SITE", the files, the context or through another website to the "SITE", the files and the context.

2.4. CONTEXT: Any visual, literary and auditory images published in the "Turkiye Klinikleri", "SITE" and/or any website or any accessible information, file, picture, number/figures, price, etc.

2.5. "USER CONTRACT": An electronically signed contract between a natural or a legal identity benefiting from special services "Turkiye Klinikleri" will provide and "Turkiye Klinikleri".

3. SCOPE OF THE SERVICES

3.1. "Turkiye Klinikleri" is completely free to determine the scope and quality of the services via the "SITE".

3.2. To benefit the services of "Turkiye Klinikleri" "SITE", the "USER" must deliver the features that will be specified by "Turkiye Klinikleri". "Turkiye Klinikleri" may change this necessity any time single-sided.

3.3. Not for a limited number, the services "Turkiye Klinikleri" will provide through the "SITE" for a certain price or for free are;

- Providing scientific articles, books and informative publications for health industry.

- Providing structural, statistical and editorial support to article preparation stage for scientific journals.

4. GENERAL PROVISIONS

4.1. "Turkiye Klinikleri" is completely free to determine which of the services and contents provided in the "SITE" will be charged.

4.2. People benefiting from the services provided by "Turkiye Klinikleri" and using the website can use the "SITE" only according to the law and only for personal reasons. Users have the criminal and civil liability for every process and action they take in the "SITE". Every USER agrees, declares and undertakes that they will not proceed by any function or action infringement of rights of "Turkiye Klinikleri"s and/or other third parties', they are the exclusive right holder on usage, processing, storage, made public and revealing any written, visual or auditory information reported to Turkiye Klinikleri" and/or "SITE" to the third parties. "USER" agrees and undertakes that s/he will not duplicate, copy, distribute, process, the pictures, text, visual and auditory images, video clips, files, databases, catalogs and lists within the "SITE", s/he will not be using these actions or with other ways to compete with "Turkiye Klinikleri", directly or indirectly.

4.3. The services provided and the context published within the "SITE" by third parties is not under the responsibility of "Turkiye Klinikleri", institutions collaborated with "Turkiye Klinikleri", "Turkiye Klinikleri" employee and directors, "Turkiye Klinikleri" authorized salespeople. Commitment to accuracy and legality of the published information, context, visual and auditory images provided by any third party are under the full responsibility of the third party. "Turkiye Klinikleri" does not promise and guarantee the safety, accuracy and legality of the services and context provided by a third party.

4.4. "USER"s cannot act against "Turkiye Klinikleri", other "USER"s and third parties by using the "SITE". "Turkiye Klinikleri" has no direct and/or indirect responsibility for any damage a third party suffered or will suffer regarding "USER"s actions on the "SITE" against the rules of the hereby "Terms of Use" and the law.

4.5. "USER"s accept and undertake that the information and context they provided to the "SITE" are accurate and legal. "Turkiye Klinikleri" is not liable and responsible for promising and guaranteeing the verification of the information and context transmitted to "Turkiye Klinikleri" by the "USER"s, or uploaded, changed and provided through the "SITE" by them and whether these information are safe, accurate and legal.

4.6. "USER"s agree and undertake that they will not perform any action leading to unfair competition, weakening the personal and commercial credit of "Turkiye Klinikleri" and a third party,  encroaching and attacking on personal rights within the "SITE" in accordance with the Turkish Commercial Code Law.

4.7. "Turkiye Klinikleri" reserves the right to change the services and the context within the "SITE"  anytime. "Turkiye Klinikleri" may use this right without any notification and timelessly. "USER"s have to make the changes and/or corrections "Turkiye Klinikleri" required immediately. Any changes and/or corrections that are required by "Turkiye Klinikleri", may be made by "Turkiye Klinikleri" when needed. Any harm, criminal and civil liability resulted or will result from changes and/or corrections required by "Turkiye Klinikleri" and were not made on time by the "USER"s belongs completely to the users.

4.8. "Turkiye Klinikleri" may give links through the "SITE" to other websites and/or "CONTEXT"s and/or folders that are outside of their control and owned and run by third parties. These links are provided for ease of reference only and do not hold qualification for support the respective web SITE or the admin or declaration or guarantee for the information inside. "Turkiye Klinikleri" does not hold any responsibility over the web-sites connected through the links on the "SITE", folders and context, the services or products on the websites provided through these links or their context.

4.9. "Turkiye Klinikleri" may use the information provided to them by the "USERS" through the "SITE" in line with the terms of the "PRIVACY POLICY" and "USER CONTRACT". It may process the information or classify and save them on a database. "Turkiye Klinikleri" may also use the USER's or visitor's identity, address, e-mail address, phone number, IP number, which sections of the "SITE" they visited, domain type, browser type, date and time information to provide statistical evaluation and customized services.

5. PROPRIETARY RIGHTS

5.1. The information accessed through this "SITE" or provided by the users legally and all the elements (including but not limited to design, text, image, html code and other codes) of the "SITE" (all of them will be called as studies tied to "Turkiye Klinikleri"s copyrights) belongs to "Turkiye Klinikleri". Users do not have the right to resell, process, share, distribute, display or give someone permission to access or to use the "Turkiye Klinikleri" services, "Turkiye Klinikleri" information and the products under copyright protection by "Turkiye Klinikleri". Within hereby "Terms of Use" unless explicitly permitted by "Turkiye Klinikleri" nobody can reproduce, process, distribute or produce or prepare any study from those under "Turkiye Klinikleri" copyright protection.

5.2. Within hereby "Terms of Use", "Turkiye Klinikleri" reserves the rights for "Turkiye Klinikleri" services, "Turkiye Klinikleri" information, the products associated with "Turkiye Klinikleri" copyrights, "Turkiye Klinikleri" trademarks, "Turkiye Klinikleri" trade looks or its all rights for other entity and information it has through this website unless it is explicitly authorized by "Turkiye Klinikleri".

6. CHANGES IN THE TERMS OF USE

"Turkiye Klinikleri" in its sole discretion may change the hereby "Terms of Use" anytime announcing within the "SITE". The changed terms of the hereby "Terms of Use" will become valid when they are announced. Hereby "Terms of Use" cannot be changed by unilateral declarations of users.

7. FORCE MAJEURE

"Turkiye Klinikleri" is not responsible for executing late or never of this hereby "Terms of Use", privacy policy and "USER Contract" in any situation legally taken into account as force majeure. Being late or failure of performance or non-defaulting of this and similar cases like this will not be the case from the viewpoint of "Turkiye Klinikleri", and "Turkiye Klinikleri" will not have any damage liability for these situations. "Force majeure" term will be regarded as outside of the concerned party's reasonable control and any situation that "Turkiye Klinikleri" cannot prevent even though it shows due diligence. Also, force majeure situations include but not limited to natural disasters, rebellion, war, strike, communication problems, infrastructure and internet failure, power cut and bad weather conditions.

8. LAW AND AUTHORISATION TO FOLLOW

Turkish Law will be applied in practicing, interpreting the hereby "Terms of Use" and managing the emerging legal relationships within this "Terms of Use" in case of finding element of foreignness, except for the rules of Turkish conflict of laws. Ankara Courts and Enforcement Offices are entitled in any controversy happened or may happen due to hereby contract.

9. CLOSING AND AGREEMENT

Hereby "Terms of Use" come into force when announced in the "SITE" by "Turkiye Klinikleri". The users are regarded to agree to hereby contract terms by using the "SITE". "Turkiye Klinikleri" may change the contract terms and the changes will be come into force by specifying the version number and the date of change on time it is published in the "SITE".

 

30.03.2014

Privacy Policy

We recommend you to read the terms of use below before you visit our website. In case you agree these terms, following our rules will be to your favor. Please read our Terms of Use thoroughly.

www.turkiyeklinikleri.com website belongs to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. and is designed in order to inform physicians in the field of health

www.turkiyeklinikleri.com cannot reach to user’s identity, address, service providers or other information. The users may send this information to the website through forms if they would like to. However, www.turkiyeklinikleri.com may collect your hardware and software information. The information consists of your IP address, browser type, operating system, domain name, access time, and related websites. www.turkiyeklinikleri.com cannot sell the provided user information (your name, e-mail address, home and work address, phone number) to the third parties, publish it publicly, or keep it in the website. Gathered information has a directing feature to be a source for the website’s visitor profile, reporting and promotion of the services.

www.turkiyeklinikleri.com uses the taken information:

-To enhance, improve and maintain the quality of the website

-To generate visitor’s profile and statistical data

-To determine the tendency of the visitors on using our website

-To send print publications/correspondences

-To send press releases or notifications through e-mail

-To generate a list for an event or competition

By using www.turkiyeklinikleri.com you are considered to agree that;

-Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. cannot be hold responsible for any user’s illegal and immoral behavior,

-Terms of use may change from time to time,

-It is not responsible for other websites’ contents it cannot control or the harms they may cause although it uses the connection they provided.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. may block the website to users in the following events:

-Information with wrong, incomplete, deceiving or immoral expressions is recorded to the website,

-Proclamation, advertisement, announcement, libelous expressions are used against natural person or legal identity,

-During various attacks to the website,

-Disruption of the website because of a virus.

Written, visual and audible materials of the website, including the code and the software are under protection by legal legislation.

Without the written consent of Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. the information on the website cannot be downloaded, changed, reproduced, copied, republished, posted or distributed.

All rights of the software and the design of the website belong to Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc.

Ortadoğu Advertisement Presentation Publishing Tourism Education Architecture Industry and Trade Inc. will be pleased to hear your comments about our terms of use. Please share the subjects you think may enrich our website or if there is any problem regarding our website.

info@turkiyeklinikleri.com